Association between the peripheral blood eosinophil counts and COVID-19: A meta-analysis.

Medicine
Rong HuangTianchun Liu

Abstract

The conclusions about the relationship between eosinophil counts and the severity of coronavirus disease 2019 (COVID-19) were controversial, so we updated the evidences and reassessed it. We searched the PubMed, Cochrane library, Excerpta Medica Database, and Web of Science to compare the eosinophil counts about non-severe disease group (mild pneumonia, moderate pneumonia, non-critical disease and recovery group) and severe disease group (severe pneumonia, critical pneumonia, critical disease and death group) in COVID-19. A total of 1228 patients from 10 studies were included. Compared with non-severe group, severe group had strikingly lower average eosinophil counts (SMD 0.65, 95% confidence intervals [CI] 0.29-1.01; P < .001). The result of subgroup analysis of different countries showed SMD 0.66, 95% CI 0.26-1.06; P < .001. Another subgroup analysis between mild-moderate pneumonia versus severe-critical pneumonia showed SMD 0.69, 95% CI 0.25-1.13; P < .001, and no significant risk of publication bias (Begg test 0.063 and Egger test 0.057) in this subgroup. The heterogeneity was substantial, but the sensitivity analyses showed no significant change when individual study was excluded, which suggested the crediblity and stablit...Continue Reading

References

Sep 11, 2018·The Journal of Allergy and Clinical Immunology. in Practice·Michael J Chusid
Oct 16, 2019·Journal of Immunology Research·Prem P Lamichhane, Amali E Samarasinghe
Feb 1, 2020·American Journal of Respiratory and Critical Care Medicine·W Graham CarlosShazia Jamil
Mar 8, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Giuseppe Lippi, Mario Plebani
Mar 13, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chuan QinDai-Shi Tian
Mar 17, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Zhongliang WangRuiguang Zhang
Apr 1, 2020·The Journal of Infectious Diseases·Fan WangYongxi Zhang
Apr 8, 2020·Médecine et maladies infectieuses·Zulvikar Syambani Ulhaq, Gita Vita Soraya
Apr 20, 2020·Journal of Thrombosis and Haemostasis : JTH·Litao ZhangZhenlu Zhang
Apr 22, 2020·QJM : Monthly Journal of the Association of Physicians·G Lippi, B M Henry
Apr 28, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Suyu SunXingzhong Hu
Apr 29, 2020·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Fang LiuXiang Zhou
May 18, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Da-Wei SunGuo-Yue Lv
May 26, 2020·Scandinavian Journal of Clinical and Laboratory Investigation·Zu-Li ZhangFeng-Zeng Li
Jun 17, 2020·Journal of Investigational Allergology & Clinical Immunology·J M Rodrigo-MuñozV Del Pozo
Jun 23, 2020·Annals of Translational Medicine·Changzheng WangChengbin Li
Jun 23, 2020·The Journal of Infection·Haipeng Zhang, Ti Wu
Jul 6, 2020·Clinical Medicine : Journal of the Royal College of Physicians of London·Vincenzo FormicaJacopo M Legramante
Jul 28, 2020·Critical Care : the Official Journal of the Critical Care Forum·Xiao-Yun ChenXiang-Qi Chen

❮ Previous
Next ❯

Citations

Dec 7, 2021·Hematology·Valencia Shihuan LongChing-Hui Sia

❮ Previous
Next ❯

Software Mentioned

Endnote X9
Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Mohammed AlareedhAhmed Nafakhi
Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Société Canadienne Des Sciences Pharmaceutiques
Mingwang JiaLichan Wu
© 2021 Meta ULC. All rights reserved