Association between the time to surgery and survival among patients with colon cancer: A population-based study

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
J A FlemmingC M Booth

Abstract

Factors associated with time-to-surgery (TTS) and survival in colon cancer has not been well studied. Cancer Care Ontario recommends surgery within 42 days of diagnosis and that 90% of patients meet this benchmark. We describe factors associated with TTS and survival in routine clinical practice. Retrospective population-based cohort study of patients receiving elective colonic resection after diagnosis of colon cancer in Ontario, Canada from 2002 to 2008 followed until 2012. Factors associated with TTS were identified using multivariate log-binomial and Quantile regression at 42 days and 90th percentiles. The association between TTS and cancer-specific (CSS) and overall survival (OS) were examined using multivariate Cox regression. 4326 patients; median age 71 years and 52% male. Median TTS was 24 days (IQR 14-37); at the 90th percentile 56 days. Factors associated with TTS ≥ 42 days and >90th percentile included older age, co-morbid illness, surgeon volume, and stage I disease (P < 0.05 for all). In patients whose TTS was either at 42 days or 90th percentile, those ≥80 years old waited two weeks longer than those <60 years, individuals with co-morbid illness waited 10 days longer than without co-morbidity, and patients with s...Continue Reading

Citations

Jan 20, 2018·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Sanjay P BagariaNabil Wasif
Aug 2, 2019·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Maude TrepanierLawrence Lee
Dec 26, 2018·Journal of Surgical Oncology·Leonardo S Lino-SilvaAbelardo Meneses-García
Jan 19, 2020·World Journal of Surgery·Yuta KumazuTakashi Oshima
Jul 2, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Scott C FligorMark P Callery
Nov 6, 2020·BMJ : British Medical Journal·Timothy P HannaAjay Aggarwal
Feb 5, 2021·The Lancet Oncology·Charlotte J L MolenaarGerrit D Slooter
Mar 14, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Thomas M WhittakerGethin L Williams
Apr 5, 2021·World Journal of Surgery·Charlotte J L MolenaarGerrit D Slooter
Dec 19, 2019·Annals of Surgery·Christof KaltenmeierSamer Tohme

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