Association between Transverse Sinus Hypoplasia and Cerebral Venous Thrombosis: A Case-Control Study

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Antonio ArauzMiguel A Barboza

Abstract

Hypoplasia of the transverse sinus (TS) is a common anatomical variation. However, the relationship between TS hypoplasia and venous thrombosis has not been studied. We analyzed the hypothesis that TS hypoplasia is a predisposing factor for ipsilateral thrombosis. We retrospectively evaluated 20 confirmed cases with isolated TS thrombosis and 43 age- and sex-matched controls. TS thrombosis and hypoplasia were diagnosed using both computed tomography and magnetic resonance venography. Hypoplasia was defined as a TS diameter less than 50% of the cross-sectional diameter of the lumen of the distal superior sagittal sinus and by a bony groove ratio less than 1.02. Univariate analysis was performed to evaluate the association between TS hypoplasia and thrombosis. There were a total of 45 hypoplastic TS: 31 (49%) left hypoplastic TS (12 (60%) cases vs 19 (44%) controls (P = .24), and 14 (22%) right hypoplastic TS (9 (45%) cases vs 5 (12%) controls (P = .003). TS hypoplasia was more frequently found in cases (n = 18, 90.0%) than in controls (n = 22, 51.2%; relative risk 1.7, confidence interval [CI] 95% 1.3-2.4, P = .003). Hypoplastic TS and ipsilateral TS thrombosis showed a significant association (P = .002 for right and P = .008 fo...Continue Reading

Citations

Jan 3, 2019·Neurological Research·Ezgi Yetim ArsavaMehmet Akif Topcuoglu
Mar 10, 2020·The Journal of Craniofacial Surgery·Satoshi TsutsumiHisato Ishii
Apr 14, 2020·Neuroradiology·Monique BoukobzaHugues Chabriat
Jul 1, 2020·Radiology Case Reports·Thi Phuong Thao HoangLouis Boyer
Aug 13, 2021·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Xiurong LiLi Shi

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