Association Between Uric Acid and Metabolic Syndrome in Elderly Women

Open Medicine
Hui-Juan WangSong-Tao Shi

Abstract

To investigate the relationship between uric acid and metabolic syndrome (MetS) in elderly women. A total of 468 women aged ≥60 years participating in a health examination were enrolled. The association between uric acid and MetS and its individual variables was evaluated by univariate and multivariate logistic regression models. A dose-response relationship was observed for the prevalence of MetS and uric acid quartiles. Subjects in the second, third and fourth quartile of uric acid had a 2.23-fold, 2.25-fold and 4.41-fold increased risk, respectively, of MetS than those in the first uric acid quartile (p for trend <0.001). Furthermore, each 1 mg/dl increment of serum uric acid level had a 1.38-fold increased risk of MetS (OR 1.38; 95% CI, 1.14-1.69; p=0.001). Our present study demonstrated that elevated uric acid was positively associated with the prevalence of MetS in elderly women. Further random control trials are needed to elucidate the effectiveness of treatment of hyperuricaemia in reducing the incidence of MetS in elderly women.

References

Jan 1, 1992·Journal of Molecular Evolution·X W WuC T Caskey
Jul 18, 2003·Current Diabetes Reports·Prakash C Deedwania
Oct 7, 2004·The American Journal of Cardiology·Giuseppe MercuroGiuseppe M C Rosano
Apr 20, 2005·Lancet·Dongfeng GuUNKNOWN InterASIA Collaborative Group
Apr 21, 2005·Kidney International·Uday M KhoslaRichard J Johnson
Oct 20, 2005·American Journal of Physiology. Renal Physiology·Takahiko NakagawaRichard J Johnson
Oct 28, 2005·Journal of the American Society of Nephrology : JASN·Duk-Hee KangRichard J Johnson
Feb 8, 2007·The Journal of Clinical Endocrinology and Metabolism·Scott M Grundy
Feb 16, 2007·Annals of Epidemiology·Seungho RyuKi Chul Sung
Mar 27, 2007·Clinical Endocrinology·G Neil ThomasUNKNOWN Hong Kong Cardiovascular Risk Factor Prevalence Study Steering Committee
Apr 13, 2007·American Journal of Physiology. Cell Physiology·Yuri Y SautinRichard J Johnson
Sep 15, 2007·Journal of the American Society of Nephrology : JASN·Sirirat ReungjuiTakahiko Nakagawa
Oct 30, 2007·The Medical Clinics of North America·Danielle Lann, Derek LeRoith
Mar 26, 2009·BioFactors·Guoyao Wu, Cynthia J Meininger
Oct 9, 2009·Autoimmunity·Christine SchornMartin Herrmann
Dec 24, 2009·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S E Perez-PozoJ López Lillo
Apr 29, 2010·Current Hypertension Reports·Rodolfo Leão BorgesMarcelo Costa Batista
Nov 1, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kazufumi NagahamaYusuke Ohya
Dec 6, 2014·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Jong-Keun LeeSung Keun Park
Dec 26, 2015·European Journal of Internal Medicine·Mehmet KanbayRichard J Johnson
Jul 13, 2017·Current Medicinal Chemistry·Francesca SantilliGiovanni Davi

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Citations

Mar 9, 2019·Environmental Science and Pollution Research International·Ram B Jain, Alan Ducatman
Dec 29, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Masaya MatsubayashiEiichiro Mori
Apr 8, 2021·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Marzieh BakhshayeshkaramKamran Bagheri Lankarani
Oct 28, 2021·Endocrinology, Diabetes & Metabolism·Farzaneh YazdiMohammad Hossein Gozashti

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