Association Between Vitamin D Insufficiency and Metabolic Syndrome in Patients With Psychotic Disorders

Psychiatry Investigation
Taeyoung YooSung-Wan Kim

Abstract

This study examined the association between vitamin D and metabolic syndrome in patients with psychotic disorders. The study enrolled 302 community-dwelling patients with psychotic disorders. Sociodemographic and clinical characteristics, including blood pressure, physical activity, and dietary habit were gathered. Laboratory examinations included vitamin D, lipid profile, fasting plasma glucose, HbA1c, liver function, and renal function. Vitamin D insufficiency was defined as <20 ng/mL. Clinical characteristics associated with vitamin D insufficiency were identified. Among the 302 participants, 236 patients (78.1%) had a vitamin D insufficiency and 97 (32.1%) had metabolic syndrome. Vitamin D insufficiency was significantly associated with the presence of metabolic syndrome (p=0.006) and hypertension (p=0.017). Significant increases in triglycerides and alanine transaminase were observed in the group with a vitamin D insufficiency (p=0.002 and 0.011, respectively). After adjusting for physical activity and dietary habit scores, vitamin D insufficiency remained significantly associated with metabolic syndrome and hypertension. Vitamin D insufficiency was associated with metabolic syndrome and was particularly associated with hi...Continue Reading

References

Aug 15, 1980·Science·A W NormanG M Grodsky
Sep 1, 2000·The American Journal of Clinical Nutrition·J WortsmanM F Holick
Jul 11, 2002·The Journal of Clinical Endocrinology and Metabolism·Anneli Seppälä-LindroosHannele Yki-Järvinen
May 21, 2003·Acta Psychiatrica Scandinavica. Supplementum·J M HaroUNKNOWN SOHO Study Group
Nov 27, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jeffrey D BrowningHelen H Hobbs
Dec 9, 2004·The American Journal of Clinical Nutrition·Bess Dawson-Hughes
Jun 23, 2005·Diabetologia·C MathieuR Bouillon
Dec 13, 2005·American Heart Journal·Charles H HennekensDaniel E Casey
Jun 1, 2006·Diabetes Research and Clinical Practice·Sang Yeoup LeeHyung Joon Yoo
Sep 27, 2006·The American Journal of Medicine·Andrea GalassiJiang He
Dec 2, 2006·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Consuelo H WilkinsJohn C Morris
Feb 9, 2007·The Journal of Steroid Biochemistry and Molecular Biology·P Lips
May 15, 2007·Medical Hypotheses·Michael BerkSeetal Dodd
Jan 9, 2008·Circulation·Thomas J WangRamachandran S Vasan
Feb 19, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·J A SugdenA D Struthers
Jun 11, 2008·Archives of Internal Medicine·Edward GiovannucciEric B Rimm
Aug 13, 2008·Archives of Internal Medicine·Michal L MelamedBrad Astor
Sep 9, 2008·The Australian and New Zealand Journal of Psychiatry·Michael BerkJulie A Pasco
Feb 18, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Andrea Z LaCroixJean Wactawski-Wende
Apr 2, 2009·The International Journal of Behavioral Nutrition and Physical Activity·Adrian BaumanUNKNOWN IPS Group
Jun 23, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A MithalUNKNOWN IOF Committee of Scientific Advisors (CSA) Nutrition Working Group
Jan 13, 2010·BMJ : British Medical Journal·Simon H S Pearce, Tim D Cheetham
Sep 8, 2010·Archives of General Psychiatry·John J McGrathPreben B Mortensen
Apr 29, 2011·The British Journal of Psychiatry : the Journal of Mental Science·Kerrie M SandersMichael Berk
Nov 9, 2011·Critical Reviews in Food Science and Nutrition·Atif B AwadMichael Valerio
Dec 20, 2011·Acta Psychiatrica Scandinavica·D VancampfortM De Hert
Jun 28, 2012·BMC Psychiatry·David B MenkesStephen A du Toit
Feb 5, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Rebecca E S AnglinSarah D McDonald
Jul 12, 2013·The Journal of Clinical Psychiatry·Patricia J MartensHeather J Prior
Feb 15, 2015·Endocrine·Eva KlingbergOla Hammarsten
Jul 28, 2016·Schizophrenia Bulletin·Stefan LeuchtJohn M Davis
Jan 28, 2017·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Nancy H LiuShekhar Saxena
Feb 12, 2017·Acta Psychiatrica Scandinavica·J J McGrath

❮ Previous
Next ❯

Software Mentioned

SPSS
IPAQ

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.