Association between work-related biomechanical risk factors and the occurrence of carpal tunnel syndrome: an overview of systematic reviews and a meta-analysis of current research

BMC Musculoskeletal Disorders
Agnessa KozakAlbert Nienhaus

Abstract

Occupational risks for carpal tunnel syndrome (CTS) have been examined in various occupations, and several systematic reviews (SRs) have been published on this topic. There has been no critical appraisal or synthesis of the evidence in the SRs. The aims of this study are (1) to synthesise the observational evidence and evaluate the methodological quality of SRs that assess the effect of biomechanical risk factors on the development of CTS in workers, (2) to provide an update of current primary research on this association, (3) to assess a potential dose-response relationship. We searched MEDLINE, EMBASE, CINAHL, the Cochrane Library and the reference lists of articles. The first step covered SRs (1998-2014), and the second step covered current primary studies (2011-2014). The methodological quality of the SRs was evaluated by using the AMSTAR-R tool; primary studies were assessed using a list of 20 items. A qualitative approach was used for synthesising evidence. In addition, we undertook a meta-analysis of the primary studies to determine risk ratios in the dose-response relationship. We identified ten SRs that covered a total of 143 original studies. Seven primary studies met the criteria for inclusion, of which four provided...Continue Reading

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Citations

Jun 22, 2017·International Archives of Occupational and Environmental Health·Roberto MeroniGuido Cavaletti
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Software Mentioned

RevMan
Excel
AMSTAR
- analysis of Observational Studies in Epidemiology ( MOOSE )
Ovid
Meta
AMSTAR - R Assessment of Multiple Systematic Reviews Revised

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