Apr 10, 2020

Nonmedical Masks in Public for Respiratory Pandemics: Droplet Retention by two-layer Textile Barrier Fully Protects Germ-free Mice from Bacteria in Droplets

BioRxiv : the Preprint Server for Biology
Alexander Rodriguez-PalaciosF. Cominelli

Abstract

Due to the shortage of masks during the pandemic, we recently demonstrated that household textiles are effective environmental droplet barriers (EDBs) with identical droplet retention potential as medical masks. To further promote the implementation of a universal community droplet reduction solution based on a synchronized encouragement/enforcement of mask utilization by the public based on widely available textiles (mask fabrication without the need for sewing machines), here we conducted a study using germ-free mice to determine to what extent textiles were effective in vivo. Using a bacterial-suspension spray simulation model of droplet ejection (mimicking a sneeze), we quantified the extent by which 100% cotton textile prevented the contamination of germ-free animals on the other side of the textile-barrier (simulating a properly worn mask). Of relevance, all mice protected with textiles remained germ-free after two sprays (inoculation dose: >600 bacterial droplet units per 56.75cm2) compared to the contamination of mice not protected by a textile (0/12 vs 6/6, Fisher`s exact, p<0.0001). In a second phase of the experiment with 12 germ-free mice exposed again to 10-fold more droplets remained germ-free, while 100% of mice ...Continue Reading

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Genome-Wide Association Study
Study
Immune Effector Cell
Inflammatory Disorder
Chronic Inflammation
Study of Epigenetics
Inflammatory Bowel Diseases
Crohn Disease
Genotype Determination
Gene Mutant

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

MedRxiv : the Preprint Server for Health Sciences
Alexander Rodriguez-PalaciosS. Ilic
Soft Matter
Gannian ZhangJ Rafael Castrejón-Pita
Acta Microbiologica Academiae Scientiarum Hungaricae
H SzeriB Radnai
Acta Microbiologica Academiae Scientiarum Hungaricae
L Berek, S Bános
© 2020 Meta ULC. All rights reserved