Association mapping of quantitative disease resistance in a natural population of loblolly pine (Pinus taeda L.).

Genetics
Tania QuesadaJ Davis

Abstract

Genetic resistance to disease incited by necrotrophic pathogens is not well understood in plants. Whereas resistance is often quantitative, there is limited information on the genes that underpin quantitative variation in disease resistance. We used a population genomic approach to identify genes in loblolly pine (Pinus taeda) that are associated with resistance to pitch canker, a disease incited by the necrotrophic pathogen Fusarium circinatum. A set of 498 largely unrelated, clonally propagated genotypes were inoculated with F. circinatum microconidia and lesion length, a measure of disease resistance, data were collected 4, 8, and 12 weeks after inoculation. Best linear unbiased prediction was used to adjust for imbalance in number of observations and to identify highly susceptible and highly resistant genotypes ("tails"). The tails were reinoculated to validate the results of the full population screen. Significant associations were detected in 10 single nucleotide polymorphisms (SNPs) (out of 3938 tested). As hypothesized for genes involved in quantitative resistance, the 10 SNPs had small effects and proposed roles in basal resistance, direct defense, and signal transduction. We also discovered associated genes with unkno...Continue Reading

References

Jan 1, 1995·Plant Molecular Biology·C A Loopstra, R R Sederoff
Oct 7, 1998·Protein Science : a Publication of the Protein Society·A M NersissianJ S Valentine
Oct 8, 1999·Fungal Genetics and Biology : FG & B·S F CovertV T McKinney
Jun 3, 2000·Genetics·J K PritchardP Donnelly
Jul 19, 2001·Nature·J L Dangl, J D Jones
Oct 11, 2001·American Journal of Human Genetics·H H GöringJ Blangero
May 22, 2002·Journal of Neuroimmunology·Sandra D'AlfonsoUNKNOWN Italian Group for the Study of Multiple Sclerosis Genetics
Apr 11, 2003·Current Psychiatry Reports·Peter McGuffinAlejandro Corsico
Sep 25, 2003·Annual Review of Plant Biology·Sherry A Flint-GarciaEdward S Buckler
Jun 29, 2004·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Alison M MorseJohn M Davis
Jul 3, 2004·Trends in Plant Science·David B Neale, Outi Savolainen
Oct 13, 2004·Proceedings of the National Academy of Sciences of the United States of America·Garth R BrownDavid B Neale
Feb 9, 2005·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Gogce C KayihanJohn M Davis
Dec 20, 2005·The Plant Journal : for Cell and Molecular Biology·Sherry A Flint-GarciaEdward S Buckler
Mar 1, 2006·Current Opinion in Biotechnology·Jianming Yu, Edward S Buckler
Oct 19, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Xianming WeiBarry Croft
Nov 17, 2006·Nature·Jonathan D G Jones, Jeffery L Dangl
Nov 18, 2006·Genetics·Santiago C González-MartínezDavid B Neale
May 29, 2007·Nature·Douglas F EastonBruce A J Ponder
Dec 7, 2007·Genome Génome / Conseil National De Recherches Canada·Jianjun ZhaoMaarten Koornneef
Feb 23, 2008·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Ju WangTed Helms
May 15, 2008·Heredity·S C González-MartínezD B Neale
Jul 5, 2008·Plant Physiology·Sandra GoritschnigXin Li
Jul 25, 2008·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Benjamin StichAlbrecht E Melchinger
Oct 3, 2008·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Silke StrackeHans-Peter Piepho
Dec 9, 2008·Trends in Plant Science·Jesse A PolandRebecca J Nelson
May 5, 2009·Genome Research·Jonathan Flint, Trudy F C Mackay
May 19, 2009·Nature Reviews. Genetics·Michael E Goddard, Ben J Hayes
Aug 8, 2009·Science·Edward S BucklerMichael D McMullen

❮ Previous
Next ❯

Citations

Nov 19, 2011·American Journal of Public Health·Muin J KhouryW David Dotson
Jan 5, 2014·Pharmacogenetics and Genomics·Susanne B Haga, Jivan Moaddeb
Apr 19, 2012·Journal of Experimental Botany·M Awais Khan, Schuyler S Korban
Dec 4, 2015·Proceedings. Biological Sciences·Isabel Rodríguez-QuilónSantiago C González-Martínez
Feb 26, 2013·Molecular Ecology Resources·Hans A Vasquez-GrossJill L Wegrzyn
Mar 13, 2012·Molecular Ecology·Thomas L ParchmanC Alex Buerkle
Nov 20, 2012·The New Phytologist·Fernando P GuerraDavid B Neale
Apr 5, 2013·The Plant Journal : for Cell and Molecular Biology·Leandro G NevesMatias Kirst
Dec 2, 2011·The New Phytologist·Andrew J EckertDavid B Neale
Mar 19, 2013·Global Change Biology·Florian J AlbertoOuti Savolainen
Sep 11, 2013·The New Phytologist·Katharina B BuddeSantiago C González-Martínez
Jan 3, 2012·Trends in Plant Science·Antoine HarfoucheGiuseppe Scarascia Mugnozza
Oct 16, 2018·The New Phytologist·Amanda R De La TorreDavid B Neale
Jan 12, 2019·Molecular Ecology·Bridget J PiculellJason D Hoeksema
Jul 13, 2020·The Plant Journal : for Cell and Molecular Biology·Matthew WeissAmanda R De La Torre
Sep 1, 2017·G3 : Genes - Genomes - Genetics·Ahmad H SallamBrian J Steffenson
Dec 23, 2016·The Journal of Heredity·Benoit TalbotStéphanie Manel
Sep 14, 2012·G3 : Genes - Genomes - Genetics·Jason A HollidaySally Aitken
Oct 13, 2018·BMC Plant Biology·Mebarek LamaraJohn J MacKay
Jul 5, 2021·Molecular Ecology·Hernán D Capador-BarretoMalin Elfstrand

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.