Association models for binding of molecules to nanostructures

The Analyst
Manuel AhumadaEmilio I Alarcon

Abstract

The interaction between nanoparticles and molecules plays a key role in determining the activity and performance of a given nanostructure. These interactions are pivotal for a variety of applications including drug delivery, surface manipulation for targeted therapies, and catalysis. However, to this day, gathering precise association parameters for the interaction of the molecules with nanostructures remains elusive and mostly imprecise. In this review, we present a critical discussion of the most commonly used techniques and models intended for determining the association of molecules with nanoparticles. Particular emphasis has been put on discussing the limitations and pitfalls related to determining association constants in this tutorial review.

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Citations

Nov 8, 2017·Proceedings of the National Academy of Sciences of the United States of America·Amanda M GoodmanNaomi J Halas
Dec 7, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·M AhumadaE I Alarcon
Apr 25, 2019·Scientific Reports·Rafaela Dos S PeinadoMonika A Coronado
May 22, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Carlos Alberto Huerta-AguilarNarinder Singh
Nov 6, 2018·Antiviral Research·Monika Aparecida CoronadoRaghuvir Krishnaswamy Arni
Jan 20, 2021·ACS Biomaterials Science & Engineering·Caitlin LazurkoEmilio I Alarcon

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