Association of Adolescent Hypertension With Future End-stage Renal Disease

JAMA Internal Medicine
Adi LeibaEhud Grossman

Abstract

Hypertension is a leading risk factor of cardiovascular morbidity and mortality. The role of nonmalignant hypertension as the sole initiating factor of end-stage renal disease (ESRD) in non-African American populations has recently been questioned. To investigate the association between hypertension and future ESRD in otherwise healthy adolescents. This retrospective cohort study examined the data of 16- to 19-year-old healthy candidates for military service in the Israel Defense Forces between January 1, 1967, and December 31, 2013. Data were obtained from the central conscription registry of the Israel Defense Forces and the ESRD registry of the Israel Ministry of Health. Participants underwent a comprehensive medical assessment prior to their military service. Individuals with evidence of renal damage or kidney-related risk factors were excluded. The data analysis was conducted from February 12, 2017, to October 16, 2018. End-stage renal disease as recorded by the Israeli ESRD registry, including hemodialysis, peritoneal dialysis, renal transplant diagnosed between January 1, 1990, and December 31, 2014. The cohort included 2 658 238 adolescents (1 596 709 [60.1%] male with a mean [SD] age of 17.4 [0.5] years), of whom 7997 ...Continue Reading

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Citations

May 28, 2020·International Journal of Environmental Research and Public Health·Katarína ŠebekováJozef Šebek
Jun 11, 2020·Pediatric Annals·Sahar Siddiqui, Rossana Malatesta-Muncher
Apr 18, 2019·Journal of Human Hypertension·Marcel Ruzicka, Swapnil Hiremath
Sep 22, 2020·World Journal of Clinical Cases·Yossy MachlufOrna Tal
Dec 4, 2019·Wiener klinische Wochenschrift·Thomas WeberUNKNOWN Österreichische Gesellschaft für Kinder- und Jugendheilkunde
Jan 4, 2021·European Heart Journal·Ramon EstruchFrancesco Cosentino
Sep 24, 2019·American Journal of Lifestyle Medicine·Shivam JoshiScott E Liebman
Mar 12, 2021·Journal of the American Society of Nephrology : JASN·Alexander J KulaNisha Bansal
Mar 13, 2021·The Lancet Child & Adolescent Health·Michael Khoury, Elaine M Urbina
Aug 3, 2021·European Urology Open Science·Sander Groen In 't WoudMichiel F Schreuder
Aug 4, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Nicole M BruntonJonathan M McGavock
Aug 20, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chang Seong KimSoo Wan Kim
Aug 28, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Sang Hyun JooKyo Sun Kim

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