Association of airborne particles, protein, and endotoxin with emergency department visits for asthma in Kyoto, Japan

Environmental Health and Preventive Medicine
Mohammad Shahriar KhanTetsushi Watanabe

Abstract

The health effects of biological aerosols on the respiratory system are unclear. The purpose of this study was to clarify the association of airborne particle, protein, and endotoxin with emergency department visits for asthma in Kyoto City, Japan. We collected data on emergency department visits at a hospital in Kyoto from September 2014 to May 2016. Fine (aerodynamic diameter ≤ 2.5 μm) and coarse (≥ 2.5 μm) particles were collected in Kyoto, and protein and endotoxin levels were analyzed. The association of the levels of particles, protein, endotoxin, and meteorological factors (temperature, relative humidity, wind speed, and air pressure) with emergency department visits for asthma was estimated. There were 1 to 15 emergency department visits for asthma per week, and the numbers of visits increased in the autumn and spring, namely many weeks in September, October, and April. Weekly concentration of protein in fine particles was markedly higher than that in coarse particles, and protein concentration in fine particles was high in spring months. Weekly endotoxin concentrations in fine and coarse particles were high in autumn months, including September 2014 and 2015. Even after adjusting for meteorological factors, the concent...Continue Reading

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Citations

Oct 5, 2019·Biological & Pharmaceutical Bulletin·Mohammad Shahriar KhanTetsushi Watanabe
Apr 17, 2020·Frontiers in Pharmacology·Lianhua CuiYuxin Zheng
Dec 19, 2019·Environmental Health and Preventive Medicine·Yoshitake NakayamaChisato Mori
Nov 30, 2019·Current Allergy and Asthma Reports·Evin HowardWanda Phipatanakul
Apr 28, 2020·Environmental Science and Pollution Research International·Ting-Ting ChenChun-Quan Ou

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Methods Mentioned

BETA
Protein Assay

Software Mentioned

Microsoft Office
SPSS Statistics

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