Association of alopecia areata with atopic dermatitis and chronic spontaneous urticaria

Allergy and Asthma Proceedings
Eli MagenNatan Kahan

Abstract

Epidemiologic studies report that alopecia areata (AA) is related to various atopic and autoimmune diseases. The purpose of this study was to identify clinical characteristics and the prevalence of comorbid conditions in Israeli patients with AA. This retrospective, matched, case-control study was based on data from an electronic patient record data base. The patients with an electronically documented diagnosis of AA were included in the AA group. The control group was randomly sampled from the remaining subjects, with a case-to-control ratio of two controls for each case. Comorbidity was compared between the study groups. A total of 1751 subjects (49.4% men and 50.6% women), ages 34.9 ± 17.8 years old, were identified. The control group consisted of 3502 age- and sex-matched subjects. The AA group was characterized by a higher blood eosinophil count (0.39 ± 0.12 cells/mm3) than the control group (0.31 ± 0.14 cells/mm3; p < 0.001). In the AA group, there was a higher prevalence of allergic rhinitis (odds ratio [OR] 2.15 [1.85-2.49]; p < 0.001), asthma (OR 1.57 [1.28-1.93]; p < 0.001), atopic dermatitis (AD) (OR 4.17 [3.18-5.47]; p < 0.001), and food allergy (OR 2.79 [1.58-4.91]; p < 0.001) than in the control group. The prevale...Continue Reading

Citations

Sep 4, 2019·Experimental Dermatology·Xingqi Zhang, Kevin J McElwee
Feb 7, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Paula KageRegina Treudler
Feb 7, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Paula KageRegina Treudler
Sep 10, 2020·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Yu-Hsun WeiMu-Hong Chen
Jul 3, 2021·Allergy, Asthma & Immunology Research·Pavel KolkhirMarcus Maurer
Aug 6, 2021·ImmunoTargets and Therapy·Poonkiat SuchonwanitCherrin Pomsoong
Oct 26, 2020·The Journal of Investigative Dermatology. Symposium Proceedings·Dustin H Marks, Maryanne M Senna
Aug 2, 2019·Skin Appendage Disorders·Calvin T SungNatasha Atanaskova Mesinkovska
Jan 19, 2022·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Dimitra Aikaterini LintzeriUlrike Blume-Peytavi

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