Association of ambient particulate matter with heart failure incidence and all-cause readmissions in Tasmania: an observational study

BMJ Open
Quan HuynhKazuaki Negishi

Abstract

We sought to investigate the relationship between air quality and heart failure (HF) incidence and rehospitalisation to elucidate whether there is a threshold in this relationship and whether this relationship differs for HF incidence and rehospitalisation. This retrospective observational study was performed in an Australian state-wide setting, where air pollution is mainly associated with wood-burning for winter heating. Data included all 1246 patients with a first-ever HF hospitalisation and their 3011 subsequent all-cause readmissions during 2009-2012. Daily particulate matter <2.5 µm (PM2.5), temperature, relative humidity and influenza infection were recorded. Poisson regression was used, with adjustment for time trend, public and school holiday and day of week. Tasmania has excellent air quality (median PM2.5=2.9 µg/m3 (IQR: 1.8-6.0)). Greater HF incidences and readmissions occurred in winter than in other seasons (p<0.001). PM2.5 was detrimentally associated with HF incidence (risk ratio (RR)=1.29 (1.15-1.42)) and weakly so with readmission (RR=1.07 (1.02-1.17)), with 1 day time lag. In multivariable analyses, PM2.5 significantly predicted HF incidence (RR=1.12 (1.01-1.24)) but not readmission (RR=0.96 (0.89-1.04)). HF ...Continue Reading

Citations

May 2, 2020·European Heart Journal Cardiovascular Imaging·Quan HuynhKazuaki Negishi
May 18, 2020·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Clifford AfoakwahJoshua Byrnes
Oct 14, 2018·International Journal of Environmental Research and Public Health·Man LiYong-Hua Hu
Oct 15, 2020·Physiology·Thomas E Taylor-Clark
Jan 9, 2021·Particle and Fibre Toxicology·Hao ChenHaiyan Tong
Jan 30, 2021·American Journal of Physiology. Heart and Circulatory Physiology·Agnes Maria LedererNandu Goswami
Aug 9, 2021·Respirology : Official Journal of the Asian Pacific Society of Respirology·Sarah M FairweatherRobert J Hancox
Jun 10, 2021·Internal Medicine Journal·Clare M WalterLuke D Knibbs

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