Association of anterior segment parameters and 5-year incident narrow angles: findings from an older Chinese population.

The British Journal of Ophthalmology
Yu JiangMingguang He

Abstract

To assess the association of anterior segment optical coherence tomography (AS-OCT) parameters and 5-year incident narrow angle in China. This was a prospective cohort study of people aged 50 and older residing in Liwan District, Guangzhou, China. Random clustering sampling was used to identify adults aged 50 years and older in Liwan District, Guangzhou. In 2008 and 2013, this study was repeated and added AS-OCT imaging under dark and light conditions. Customised software (ZAAP) was used to analyse horizontal AS-OCT scans. Angle opening distance (AOD), trabecular iris space area (TISA), anterior chamber volume (ACV) and maximal iris thickness (ITM) were measured. Multiple logistic regression analysis models were used to investigate the associations of the final angle status with baseline AS-OCT parameters. ORs and 95% CIs were calculated. Of the 220 subjects with eligible AS-OCT images and gonioscopic results in 2008, the response rate was 77.3%. A total of 27 (15.9%) subjects developed narrow angles and 143 (84.1%) had open angles on gonioscopy in 2013. Subjects developed narrow angles had greater spherical equivalent and shallower anterior chamber depth, smaller angle parameters, thicker IT750 and ITM, smaller anterior chambe...Continue Reading

References

Mar 15, 1993·American Journal of Ophthalmology·J T WilenskyR Anderson
Jan 30, 2002·The British Journal of Ophthalmology·Paul J FosterGordon J Johnson
Jun 27, 2006·Investigative Ophthalmology & Visual Science·Mingguang HePeng T Khaw
Dec 25, 2007·The British Journal of Ophthalmology·J L Y YipW Nolan
Oct 10, 2009·Ophthalmology·Bingsong WangTin Aung
Feb 2, 2010·Ophthalmology·Harry A Quigley
Jun 10, 2010·The British Journal of Ophthalmology·B-S WangT Aung
Nov 3, 2010·Ophthalmology·Monisha E NongpiurTin Aung
Jul 29, 2011·Clinical & Experimental Ophthalmology·Dandan WangShan Lin
Oct 26, 2011·Investigative Ophthalmology & Visual Science·Marcus AngJodhbir S Mehta
Nov 29, 2011·Ophthalmology·Li-Lian FooTin Aung
Mar 17, 2012·Ophthalmology·Chelvin C SngTin Aung
Apr 3, 2012·American Journal of Ophthalmology·Gavin S TanTin Aung
Jun 30, 2012·Investigative Ophthalmology & Visual Science·Deborah K L TanJodhbir S Mehta
Apr 26, 2014·Investigative Ophthalmology & Visual Science·Ye ZhangNing Li Wang
May 23, 2014·Investigative Ophthalmology & Visual Science·Jong Rak LeeSeungbong Han
Jan 13, 2015·Investigative Ophthalmology & Visual Science·Ye ZhangNing Li Wang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.