Association of antioxidant monophenolic compounds with β-cyclodextrin-functionalized cellulose and starch substrates.

Carbohydrate Polymers
Roberto AguadoArtur J M Valente

Abstract

Polysaccharide substrates loaded with antioxidant and antimicrobial compounds, effectively protected by cyclodextrin moieties, can be a long-lasting solution to confer certain properties to fabrics, paper and other materials. β-Cyclodextrin was attached to α-cellulose, bleached pulp and starch by a two-step esterification with a tetracarboxylic acid. The resulting derivatives were characterized by spectroscopy, thermal degradation analysis and capability of phenolphthalein inclusion. The carriers, containing between 89 and 171 μmol of β-cyclodextrin per gram, were loaded with carvacrol, cuminaldehyde, cinnamaldehyde and hydroxytyrosol. From a stoichiometric addition, the percentage of compound retained ranged from 49% (hydroxytyrosol in pulp-cyclodextrin) to 92% (carvacrol in starch-cyclodextrin). Finally, the release rate to aqueous ethanol was measured over eight days and fitted to kinetic models. From the analysis of the mean dissolution time, it can be concluded that inserting β-cyclodextrin units enhanced the long-term holding of phenolic active compounds in carbohydrate matrices.

References

Jul 1, 1993·Pharmaceutical Research·J E Möckel, B C Lippold
Apr 12, 2001·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·P Costa, J M Sousa Lobo
Feb 19, 2002·Chemical Reviews·József Szejtli
May 7, 2005·Langmuir : the ACS Journal of Surfaces and Colloids·Denilson Da Silva PerezKarim Mazeau
Dec 19, 2006·American Journal of Physiology. Heart and Circulatory Physiology·S J RietjensG R M M Haenen
Nov 3, 2010·The Journal of Pharmacy and Pharmacology·Thorsteinn Loftsson, Marcus E Brewster
Mar 8, 2013·Carbohydrate Polymers·B MedronhoA J M Valente
Sep 10, 2013·Advances in Colloid and Interface Science·Artur J M Valente, Olle Söderman
Aug 5, 2014·Colloids and Surfaces. B, Biointerfaces·Danielly L A SittaAdley F Rubira
Feb 27, 2016·Carbohydrate Polymers·Manuela MihailiasaFrancesco Trotta
May 14, 2016·International Journal of Biological Macromolecules·Shumin LiuHuihua Huang
Nov 16, 2017·Nucleic Acids Research·David S WishartAugustin Scalbert
Jan 18, 2018·International Journal of Biological Macromolecules·Nabil A IbrahimEman M Mabrouk
May 13, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Phennapha SaokhamThorsteinn Loftsson
Jul 22, 2018·Frontiers in Chemistry·Tânia F CovaArtur J M Valente
Mar 26, 2019·Colloids and Surfaces. B, Biointerfaces·Diana CostaArtur J M Valente
Jun 15, 2019·Carbohydrate Polymers·Ana M AresCarmen Alvarez-Lorenzo

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