PMID: 1810979Dec 1, 1991Paper

Association of autoimmunity and cicatricial pemphigoid: is there an immunogenetic basis?

Journal of the American Academy of Dermatology
M NayarC J Taylor

Abstract

A group of 34 patients with cicatricial pemphigoid was investigated for the presence of autoimmune disorders. Thirty-two percent of patients had autoimmune disease compared with 7% in the control population, a highly significant difference (p less than 0.002). Circulating autoantibodies were also significantly more common in patients (p less than 0.05). Twenty-four patients with cicatricial pemphigoid were typed for HLA. A statistically significant increase in the frequency of DR4 and DQw3 antigens was observed in these patients. These findings suggest a possible genetic basis for the autoimmune association and predisposition for development of cicatricial pemphigoid.

References

Mar 1, 1978·Archives of Dermatology·G T Spigel, R K Winkelmann
Feb 1, 1989·Current Eye Research·M M ZaltasC S Foster
Jun 1, 1974·American Journal of Ophthalmology·S R Waltman, D Yarian
Sep 1, 1980·Arthritis and Rheumatism·C C PapaioannouF C McDuffie

❮ Previous
Next ❯

Citations

May 8, 1999·The British Journal of Dermatology·G KirtschigR Happle
Aug 1, 1993·Journal of the American Academy of Dermatology·G TaylorK Welch
May 21, 2011·Acta Ophthalmologica·Fahd AnzaarC Stephen Foster
May 15, 2009·Clinical and Experimental Dermatology·M MalikA R Ahmed
Nov 30, 2004·Dental Clinics of North America·Thomas P Sollecito, Ernesta Parisi
Jul 3, 2004·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·W-K Syn, M M Ahmed
Oct 1, 1993·Clinics in Dermatology·N Mobini, A R Ahmed
Sep 7, 2007·The British Journal of Oral & Maxillofacial Surgery·Crispian Scully, Lorenzo Lo Muzio
Sep 26, 2001·Acta Odontologica Scandinavica·S J ChallacombeM M Black
Mar 1, 1996·The British Journal of Dermatology·P MarrenF Wojnarowska
Jun 30, 2005·Oral Diseases·J BaganC Scully
Oct 3, 2009·The Journal of Rheumatology·Gabriela Fernanda Mora
Dec 16, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M M HoltscheE Schmidt
May 1, 1995·The British Journal of Dermatology·L Poskitt, F Wojnarowska
Feb 1, 1995·The British Journal of Dermatology·P MarrenF Wojnarowska
Feb 20, 2021·European Journal of Ophthalmology·Carlos Cifuentes-GonzálezAlejandra de-la-Torre
Sep 27, 2000·Journal of the American Academy of Dermatology·T E Fleming, N J Korman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Oral Surgery, Oral Medicine, and Oral Pathology
V E Urbanek, L Cohen
International Journal of Dermatology
A R AhmedH Pitt
Dermatologic Clinics
D F MutasimG J Anhalt
International Journal of Dermatology
Katarzyna WoźniakCezary Kowalewski
© 2021 Meta ULC. All rights reserved