Association of Blood Cadmium Level with Metabolic Syndrome After Adjustment for Confounding by Serum Ferritin and Other Factors: 2008-2012 Korean National Health and Nutrition Examination Survey

Biological Trace Element Research
Byung-Kook Lee, Yangho Kim

Abstract

We examined the association of metabolic syndrome (MS) with blood levels of cadmium (Cd), lead (Pb), and mercury (Hg) using adjustment for confounding by serum ferritin, in a representative sample of the adult population of South Korea. This cross-sectional study enrolled subjects who were at least 20 years old, completed the health examination survey, and had blood measurements of Pb, Cd, and Hg. In males, adjusted odds ratios (ORs) indicated that a doubling of blood Cd resulted in a 26.4-31.0 % increased risk of MS, and subjects in the highest tertile of blood Cd were 35.8 % more likely to have MS than those in the lowest tertile after adjustment for blood Pb, blood Hg, and serum ferritin. Serum ferritin was also associated with MS. No significant results were observed in females. There were no significant associations of MS with blood Pb or blood Hg. The present study confirms our previous findings, which had a smaller sample size and a shorter study period.

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Citations

Jun 18, 2016·Environmental Science and Pollution Research International·Xiaomin NieYingli Lu
Jul 13, 2016·Physiological Reports·Joshua D ChandlerDean P Jones
Mar 3, 2018·Biological Trace Element Research·Margarita G SkalnayaAlexey A Tinkov
Feb 21, 2018·Current Environmental Health Reports·Antonio PlanchartCarolyn J Mattingly
Oct 17, 2017·Annals of Occupational and Environmental Medicine·Hyun Chan AnYangho Kim
Jul 2, 2020·International Journal of Environmental Research and Public Health·Sunil Kumar KasundriyaAshish Pathak
Apr 5, 2017·Scientific Reports·Honglin SunYingli Lu
Jun 16, 2019·International Journal of Environmental Research and Public Health·Jaeouk AhnYangho Kim
Jan 20, 2021·Journal of Korean Medical Science·Bok Hyun ParkYangho Kim
Jul 21, 2021·Menopause : the Journal of the North American Menopause Society·Hai Duc Nguyen, Min-Sun Kim
Sep 29, 2021·Menopause : the Journal of the North American Menopause Society·Hai Duc NguyenMin-Sun Kim

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