Association of blood glucose with 30-day mortality in patients with intracerebral hemorrhage undergoing neurosurgical treatment.

British Journal of Neurosurgery
Wei ChenChao You

Abstract

Published studies have shown hyperglycemia is associated with poor outcome in patients with intracerebral hemorrhage (ICH). However, the association between blood glucose and outcome in surgical ICH patients is unknown. In the present study, we sought to evaluate the predictive value of admission and postoperative glucose for 30-day outcome in patients with ICH undergoing neurosurgical treatment. We retrospectively studied acute ICH patients who underwent neurosurgical treatment at a tertiary care hospital between January 2013 and December 2018. Patient demographics, clinical and radiological data were recorded. Serum glucose was measured at admission and after surgery. Receiver operating characteristic curves were used to evaluate the predictive power of important predictors. Multivariable logistic regression analyses were performed to identify independent factors of 30-day mortality. The present analysis included 344 patients (66.3% male, mean age 59.1 years). Elevated admission glucose (odds ratio [OR] 1.11; 95% confidence interval [CI] 1.03-1.20; p = .007) and postoperative glucose (OR 1.18, 95% CI 1.06-1.31; p = .003) were independently associated with increased 30-day mortality. There was no significant difference in pred...Continue Reading

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