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Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1

Molecular and Cellular Biology

Dec 1, 2005

Inmaculada Hernández-MuñozMaarten Van Lohuizen

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Abstract

Polycomb group (PcG) proteins are epigenetic chromatin modifiers involved in heritable gene repression. Two main PcG complexes have been characterized. Polycomb repressive complex 2 (PRC2) is thought to be involved in the initiation of gene silencing, whereas Polycomb repressive complex...read more

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Dnmt1 protein, rat
Study of Epigenetics
Complex (molecular entity)
Regulation of Chromatin Silencing
BMI1 protein, human
S Phase
Histone Deacetylase Activity
Heterochromatin
DNMT1 gene
Transcription Initiation
Paper Details
References
  • References61
  • Citations95
12345...

Association of BMI1 with polycomb bodies is dynamic and requires PRC2/EZH2 and the maintenance DNA methyltransferase DNMT1

Molecular and Cellular Biology

Dec 1, 2005

Inmaculada Hernández-MuñozMaarten Van Lohuizen

PMID: 16314526

DOI: 10.1128/mcb.25.24.11047-11058.2005

Abstract

Polycomb group (PcG) proteins are epigenetic chromatin modifiers involved in heritable gene repression. Two main PcG complexes have been characterized. Polycomb repressive complex 2 (PRC2) is thought to be involved in the initiation of gene silencing, whereas Polycomb repressive complex...read more

Mentioned in this Paper

Dnmt1 protein, rat
Study of Epigenetics
Complex (molecular entity)
Regulation of Chromatin Silencing
BMI1 protein, human
Paper Details
References
  • References61
  • Citations95
12345...

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