Association of body composition and blood pressure categories with retinal vessel diameters in primary school children

Hypertension Research : Official Journal of the Japanese Society of Hypertension
K ImhofH Hanssen

Abstract

Alterations in retinal vessel diameters have been shown to be predictive of cardiovascular risk in adults and children. The aim of our study was to examine the association of body composition and blood pressure (BP) categories with retinal vessel diameters in school children. We examined anthropometric parameters, BP and retinal arteriolar (CRAE) and venular (CRVE) diameters as well as the arteriolar-to-venular diameter ratio (AVR) in 391 children (age: 7.3, s.d. 0.4). Differences between the lowest and highest BP quartiles indicated that higher systolic and diastolic BP were associated with narrower CRAE (P<0.001 for both). Children in the highest weight quartile had narrower CRAE compared with the lowest quartile (P=0.05). In the regression analysis, systolic and diastolic BP were associated with arteriolar narrowing (-0.4 measuring units (mu) per mm Hg, 95% confidence interval: [-0.6; -0.3] and -0.6 mu per mm Hg [-0.7; -0.4], respectively; P<0.001 for both). An independent association was found for diastolic BP only. Compared with normotensives (NT; 74.4% of cohort), arteriolar narrowing was already seen in children categorized as pre-hypertensive (PHT) (11.5% of cohort), which was similar to HT children (14.1% of cohort) (N...Continue Reading

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Citations

Jan 13, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ana Díez-FernándezVicente Martínez-Vizcaíno
Oct 31, 2017·The Open Ophthalmology Journal·Daniela S SchuhManuel Ap Vilela
Jul 1, 2020·Hypertension·Giulia LonaHenner Hanssen
Oct 26, 2018·Arteriosclerosis, Thrombosis, and Vascular Biology·Line SletnerMark Hanson
Aug 19, 2018·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Adam Domonkos TarnokiGiacomo Pucci
Aug 8, 2021·International Journal of Environmental Research and Public Health·Giulia LonaHenner Hanssen
May 11, 2018·Pediatrics·Sabrina KöchliHenner Hanssen

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