Association of cardiomyopathy with adverse cardiac events in pregnant women at the time of delivery

JACC. Heart Failure
Fabio V LimaKathleen Stergiopoulos

Abstract

The aim of this study was to determine the predictors of adverse events in pregnant women with cardiomyopathy (CDM) and CDM subtypes at the time of delivery. Investigation of patients' characteristics and outcomes in women with CDM at the time of delivery has been limited. The Healthcare Cost and Utilization Project's National Inpatient Sample was screened for hospital admissions for delivery in pregnant women with CDM from 2006 to 2010. Clinical characteristics and maternal outcomes were identified in women with and without CDM and in CDM subtypes. The primary outcome of interest was major adverse clinical events (MACE), a composite of in-hospital death, acute myocardial infarction, heart failure, arrhythmia, cerebrovascular event, or embolic event. Our study population comprised 2,078 patients with CDM and 4,438,439 patients without CDM. Of those with CDM, 52 (2.5%) were hypertrophic, 1,039 (50.0%) were peripartum, and 987 (47.5%) were classified as other. Women with CDM were older, white, and insured by Medicaid. MACE rates were significantly higher in women with peripartum CDM (46%), compared with hypertrophic CDM (23%) and all others (39%) (p < 0.001). In multivariable analysis, the presence of peripartum cardiomyopathy (o...Continue Reading

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Citations

Apr 16, 2016·Archives of Cardiovascular Diseases·Fabio V LimaKathleen Stergiopoulos
May 31, 2016·The American Journal of Cardiology·Paraskevi Koutrolou-SotiropoulouKathleen Stergiopoulos
Jun 30, 2016·The New England Journal of Medicine·James S WareZoltan Arany
Jul 23, 2016·Journal of the American College of Cardiology·Uri ElkayamCandice K Silverside
Oct 27, 2017·Journal of the American Heart Association·Erin ThomasKathleen Stergiopoulos
Jul 12, 2017·Circulation·Kathleen StergiopoulosJie Yang
Jan 14, 2018·Circulation. Heart Failure·Mulubrhan F MogosJoan E Briller
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May 7, 2019·Journal of the American Heart Association·Kathleen StergiopoulosJaved Butler
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Sep 20, 2019·Current Emergency and Hospital Medicine Reports·Lindsay C BallardBory Kea
Jun 30, 2016·The New England Journal of Medicine·Kathleen StergiopoulosJie Yang
Dec 21, 2018·Journal of the American Heart Association·Amanda OwensKathleen Stergiopoulos
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Jan 14, 2021·Heart Failure Reviews·Nivedita Jha, Ajay Kumar Jha
Jul 15, 2021·Journal of the American Heart Association·Rachel A BrightKathleen Stergiopoulos

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