Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia

JAMA : the Journal of the American Medical Association
Cécilia SamieriJean-Philippe Empana

Abstract

Evidence is limited regarding the relation between cardiovascular health level and dementia risk. To investigate the association between cardiovascular health level, defined using the 7-item tool from the American Heart Association (AHA), and risk of dementia and cognitive decline in older persons. Population-based cohort study of persons aged 65 years or older from Bordeaux, Dijon, and Montpellier, France, without history of cardiovascular diseases or dementia at baseline who underwent repeated in-person neuropsychological testing (January 1999-July 2016) and systematic detection of incident dementia (date of final follow-up, July 26, 2016). The number of the AHA's Life's Simple 7 metrics at recommended optimal level (nonsmoking, body mass index <25, regular physical activity, eating fish twice a week or more and fruits and vegetables at least 3 times a day, cholesterol <200 mg/dL [untreated], fasting glucose <100 mg/dL [untreated], and blood pressure <120/80 mm Hg [untreated]; score range, 0-7) and a global cardiovascular health score (range, 0-14; poor, intermediate, and optimal levels of each metric assigned a value of 0, 1, and 2, respectively). Incident dementia validated by an expert committee and change in a composite s...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Oct 1, 1973·The British Journal of Psychiatry : the Journal of Mental Science·B Isaacs, A T Kennie
Oct 1, 1955·Journal of Consulting Psychology·R M REITAN
Nov 14, 2007·Neurology·P Barberger-GateauA Alpérovitch
Apr 30, 2009·Dementia and Geriatric Cognitive Disorders·Laure CarcaillonJean-François Dartigues
Jul 4, 2009·American Journal of Epidemiology·Séverine SabiaArchana Singh-Manoux
Jan 22, 2010·Circulation·Donald M Lloyd-JonesUNKNOWN American Heart Association Strategic Planning Task Force and Statistics Committee
Feb 28, 2013·Annals of Neurology·Jared P ReisKristine Yaffe
May 24, 2013·Statistical Methods in Medical Research·Célia TourainePierre Joly
Mar 18, 2016·Journal of the American Heart Association·Hannah GardenerRalph L Sacco
Apr 14, 2016·Stroke; a Journal of Cerebral Circulation·Matthew P PaseSudha Seshadri
Jun 24, 2017·Journal of the American College of Cardiology·Bamba GayeJean-Philippe Empana
Jul 25, 2017·Lancet·Gill LivingstonNaaheed Mukadam
Sep 9, 2017·Stroke; a Journal of Cerebral Circulation·Philip B GorelickUNKNOWN American Heart Association/American Stroke Association
Dec 22, 2017·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Hector M GonzálezThomas H Mosley

❮ Previous
Next ❯

Citations

Nov 10, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Joanne C FeeneyRose Anne Kenny
Dec 19, 2018·JAMA : the Journal of the American Medical Association·Cécilia Samieri, Jean-Philippe Empana
Dec 19, 2018·JAMA : the Journal of the American Medical Association·Robert H Howland
Feb 5, 2019·Climacteric : the Journal of the International Menopause Society·C A Stuenkel
Oct 17, 2019·Annual Review of Physiology·T Michael De Silva, Frank M Faraci
Mar 12, 2020·Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Oct 15, 2018·Aging·Stefano L Sensi
Sep 3, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Y J JeonH C Kim
Dec 29, 2018·Journal of the American Heart Association·Thanh-Huyen T VuNorrina B Allen
Mar 12, 2019·European Heart Journal·Simon R CoxIan J Deary
Jan 23, 2019·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Vladimir Hachinski
Dec 24, 2019·Clinical Hypertension·Masaki Mogi
Aug 6, 2019·Frontiers in Aging Neuroscience·Gerd Kempermann
Sep 14, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C K SuemotoI M Bensenor
Nov 29, 2020·Journal of Cross-cultural Gerontology·Silvia Mejia-ArangoCarlos A Cano-Gutierrez
Nov 27, 2020·BMC Cardiovascular Disorders·Tian-Wen HanYun-Dai Chen
Nov 30, 2020·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Chioun LeeJennifer M Boylan
Aug 10, 2020·American Journal of Obstetrics and Gynecology·Amanda M PerakUNKNOWN Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cooperative Research Group
Nov 17, 2020·Frontiers in Aging Neuroscience·Natalia SalvadoresFelipe A Court
Oct 23, 2020·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Aline ThomasCécilia Samieri
Feb 19, 2021·Environmental Science and Pollution Research International·Yeong Jun JuSoon Young Lee
Feb 17, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Noor E TaamsPieter A van Doorn
Mar 24, 2021·Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Mar 23, 2021·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Rainer MalikMartin Dichgans
May 4, 2021·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Jing GuoYian Gu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.