Association of Central Obesity with Sex Hormonebinding Globulin: A Cross-sectional Study of 1166 Chinese Men

Open Medicine
Fangwei LiuYuanzhong Zhou

Abstract

Background Both sex hormone-binding globulin and central obesity have been found to be associated with metabolic and cardiovascular diseases. However, the direct relation between sex hormone-binding globulin and central obesity has not been demonstrated. Methodology We performed a cross-sectional study of 1166 male participants from Zunyi, Guizhou, western China, in 2013. Each participant completed a questionnaire and had a brief clinical exam with a fasting blood sample taken. All blood samples underwent standard laboratory testing for sex hormone-binding globulin. Level of serum sex hormone-binding globulin was compared by demographic characteristics, and multiple linear regression was used to evaluate the independent association of variables and sex hormone-binding globulin level. Results The mean serum level of sex hormone-binding globulin was increased in old-aged men (older than 40 years; mean 44.68±20.58 nmol/L), low diastolic blood pressure (<90mmHg; 43.76±20.50 nmol/L), waist-to-height ratio <0.5 (48.73±20.59 nmol/L), no education (52.36±22.91 nmol/L), farm occupation (43.58±20.60nmol/L), non-alcohol or former user (44.78±20.94 nmol/L) and long-term medication history (44.79±21.50 nmol/L). Factors independently associa...Continue Reading

References

Feb 22, 2007·European Heart Journal·Lisa de las FuentesVíctor G Dávila-Román
Nov 10, 2007·The Journal of Clinical Investigation·David M SelvaGeoffrey L Hammond
Feb 7, 2008·Central European Journal of Public Health·Hynek PikhartMichael Marmot
Sep 30, 2009·Molecular and Cellular Endocrinology·Michel PugeatCatherine Grenot
Nov 24, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·M AshwellS Gibson
Jun 20, 2012·European Journal of Preventive Cardiology·Robin HaringHenri Wallaschofski
Mar 1, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·Z XuW Xu
Sep 10, 2014·JACC. Heart Failure·Peter WohlfahrtBarry A Borlaug

❮ Previous
Next ❯

Methods Mentioned

BETA
transgenic

Software Mentioned

SPSS

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.