Association of Change in Iris Vessel Density in Optical Coherence Tomography Angiography With Anterior Segment Ischemia After Strabismus Surgery

JAMA Ophthalmology
Federico G VelezStacy L Pineles

Abstract

Anterior segment ischemia (ASI) is a rare but potentially serious complication of strabismus surgery. Indocyanine green angiography and fluorescein angiography have been used to reveal iris-filling defects for clinicians considering a patient's risk of ASI. However, both are limited by invasive and time-consuming nature and potential adverse effects. Recently, optic coherence tomography angiography (OCT-A) has been introduced and used to image iris vasculature in individuals without abnormalities. To determine the use of iris OCT-A for patients undergoing strabismus surgery and who are at risk for ASI. This prospective case series study took place in an academic center. Adults undergoing strabismus surgery on at least 1 vertical muscle were prospectively recruited. The study took place from June to November 2017, and analysis began in January 2018. Indocyanine green angiography and OCT-A of the iris preoperatively and 1 day postoperatively. A masked examiner evaluated all images and determined whether any filling defects were present qualitatively (lack of perfusion) and quantitatively (for OCT-A using internal software to calculate vessel density). Ten eyes of 9 individuals (mean [SD] age, 63 [11] years) were included. Two ind...Continue Reading

References

Feb 13, 2001·The British Journal of Ophthalmology·T K ChanD Thayer
Oct 25, 2014·The British Journal of Ophthalmology·Erica Z OltraFederico G Velez
Jul 15, 2015·American Journal of Ophthalmology·Laura KuehleweinDavid Sarraf
Dec 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Davide AllegriniAlfredo Pece

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Citations

Jun 13, 2019·Seminars in Ophthalmology·Yusra Siddiqui, Jia Yin
Oct 3, 2020·Translational Biophotonics·Yan LiZhongping Chen
Aug 28, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Renyi XieMei Yang
Jul 28, 2020·Journal of Ophthalmology·Dayane Cristine IssahoMonica Fialho Cronemberger
Aug 21, 2020·The British Journal of Ophthalmology·Marcus AngLeopold Schmetterer
Jan 27, 2021·Journal of Clinical Medicine·Yoshio HiranoYuichiro Ogura
Feb 6, 2021·BMJ Case Reports·Jason A GoldsmithRony R Sayegh
Jul 17, 2021·European Journal of Ophthalmology·Stefano LucentiniMineo Kondo
Dec 30, 2021·International Ophthalmology Clinics·Taher K EleiwaShazia F Ali

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