Association of Chest CT-Based Quantitative Measures of Muscle and Fat with Post-Lung Transplant Survival and Morbidity: A Single Institutional Retrospective Cohort Study in Korean Population

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Young Hoon ChoSang Bum Hong

Abstract

Abnormal body composition is an important modifiable risk factor in lung transplantation. Therefore, precise quantification of different body components, including muscle and fat, may play an important role in optimizing outcomes in lung transplant patients. The purpose of the study was to investigate the prognostic significance of muscle and subcutaneous fat mass measured on chest CT with regard to lung transplantation survival and other post-transplant outcomes. The study population included 45 consecutive adult lung transplant recipients (mean age of 47.9 ± 12.1 years; 31 males and 14 females) between 2011 and 2017. Preoperative cross-sectional areas of muscle and subcutaneous fat were semi-automatically measured on axial CT images at the level of the 12th thoracic vertebra (T12). Additional normalized indexed parameters, adjusted for either height or weight, were obtained. Associations of quantitative parameters with survival and various other post-transplant outcomes were evaluated. Of the 45 patients included in the present study, 10 mortalities were observed during the follow-up period. Patients with relative sarcopenia (RS) classified based on height-adjusted muscle area with a cut-off value of 28.07 cm²/m² demonstrated...Continue Reading

References

May 1, 1986·The New England Journal of Medicine·UNKNOWN Toronto Lung Transplant Group
Mar 21, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·J MadillUNKNOWN Toronto Lung Transplant Program
Apr 4, 2001·JPEN. Journal of Parenteral and Enteral Nutrition·U G KyleC Pichard
Mar 28, 2003·Transplantation·Ursula G KyleClaude Pichard
Apr 15, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·T M EganF L Grover
May 1, 2008·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·G MauryT Troosters
Oct 17, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Marina MourtzakisVickie E Baracos
Oct 22, 2008·Transplantation Proceedings·S J HaamH C Paik
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
Jul 31, 2010·Journal of the American College of Surgeons·Michael J EnglesbeChristopher J Sonnenday
Mar 19, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Elani StrejaKamyar Kalantar-Zadeh
Jan 31, 2012·Expert Review of Respiratory Medicine·Jaime L Hook, David J Lederer
May 9, 2012·Transplantation Proceedings·H C PaikS H Jheon
Aug 21, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Andrea DiMartiniPaulo Fontes
Oct 24, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Robert W KrellPreeti N Malani
Jul 22, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Dmitry RozenbergSunita Mathur
Sep 19, 2014·American Journal of Respiratory and Critical Care Medicine·Jonathan P SingerDavid J Lederer
Dec 4, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G MalietzisJ T Jenkins
Oct 12, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Roger D YusenJosef Stehlik
Jan 23, 2016·The Annals of Thoracic Surgery·Thomas WeigNikolaus Kneidinger
Jul 2, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Eun Young KimJeong Ho Kim
Feb 15, 2017·Journal of Physiological Anthropology·Taishi FurushimaKiyoshi Sanada
Apr 9, 2017·Transplant International : Official Journal of the European Society for Organ Transplantation·Dmitry RozenbergLianne G Singer
Jul 25, 2017·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Frédéric PamoukdjianElena Paillaud
Sep 22, 2017·Journal of Thoracic Disease·Gabriel Thabut, Herve Mal
Feb 13, 2018·The Korean Journal of Thoracic and Cardiovascular Surgery·Yong Ho JeongUNKNOWN Asan Medical Center Lung Transplantation Team

❮ Previous
Next ❯

Citations

Apr 26, 2020·Current Opinion in Organ Transplantation·Rhea VarugheseLianne G Singer
Sep 30, 2020·Seminars in Musculoskeletal Radiology·Robert HemkeMartin Torriani
Sep 25, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Dmitry RozenbergSunita Mathur
Nov 26, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yeon Hyeon Choe
Feb 16, 2021·American Journal of Physical Medicine & Rehabilitation·Paulina Moctezuma-VelázquezCarlos Moctezuma-Velázquez
Aug 26, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Seong Ho ParkSeo Young Park
Mar 6, 2021·The Annals of Thoracic Surgery·Indranil BalkiDmitry Rozenberg

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.