Association of childhood croup and increased incidence of airway hyperreactivity in adulthood

Journal of Education and Health Promotion
Mohammadreza ModaresiMohsen Reisi

Abstract

Some evidence suggests that childhood croup could be associated with increased incidence of adulthood bronchial reactivity, but its significance is uncertain. The aim of the present study was to evaluate the long-term outcome of early life croup. This case-control study was conducted in 2010-2012 in Isfahan, Iran. The case group consisted of 164 adolescents with a history of severe croup in early life and an equal number of healthy controls without any history of croup or other chronic or recurrent respiratory diseases. The two groups were compared according to pulmonary function tests and bronchial reactivity (exercise challenge test). Statistical analyses were performed using the SPSS software package, version 20 (SPSS Inc., Chicago, IL, USA). P < 0.05 was considered significant. Baseline spirometric values (forced expiratory volume in 1st s (FEV1), forced volume capacity (FVC), FEV1/FVC, and forced expiratory flow at 25%-75% (FEF25-75) were similar in case and control groups. A reduction in FEV1 and FEF25-75 after exercise challenge test was seen in 9% and 12.8% of patients, respectively, whereas this was reduced in only 4.2% and 6.1% of the controls (P = 0.034 and P = 0.021, respectively). Our findings suggest that childhoo...Continue Reading

Software Mentioned

SPSS

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Dermatology : International Journal for Clinical and Investigative Dermatology
Didem Didar BalciMehmet Ugur Inan
Clinical and Translational Allergy
Mônica Versiani Nunes Pinheiro de QueirozLaura Maria de Lima Belizário Facury Lasmar
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
Y J JungY-M Oh
International Journal of Occupational Safety and Ergonomics : JOSE
Farideh GolbabaeiBehnam Dinari
© 2022 Meta ULC. All rights reserved