PMID: 8972677Dec 1, 1996Paper

Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma

Epidemiology and Infection
D HahnP Saikku

Abstract

To determine whether recently diagnosed adult-onset asthma is associated with serologic evidence of chronic Chlamydia pneumoniae infection, we performed a case-control study in a primary care clinic of cases with asthma (25 adults reporting first symptoms of asthma within 2 years of enrollment) and 45 concurrently enrolled sex and age (+/- 10 years) matched non-asthmatic controls with normal pulmonary function. C. pneumoniae-specific IgA, IgG and IgG4 antibodies, and circulating immune complexes (CIC) were measured by microimmunofluorescence testing. Results showed that frequencies of IgG titres > or = 16 (92%), IgG4 titres > or = 16 (20%) and CIC > or = 4 (60%) in asthma patients were not significantly different from those of controls. However, asthmatics had a significantly higher prevalence of C. pneumoniae-specific IgA titres > or = 10 (72% of cases vs 44% of controls, P < 0.05). After adjustment for the effects of age, sex and smoking, the odds ratio for an association of IgA and asthma was 3.7 (95% confidence interval 1.2-11.5). We conclude that recently symptomatic reversible airway obstruction in adults is associated with the presence of C. pneumoniae-specific IgA antibodies, a proposed indicator of chronic respiratory ...Continue Reading

References

Aug 1, 1979·Journal of Clinical Microbiology·S P WangJ T Grayston
Jan 1, 1978·Respiration; International Review of Thoracic Diseases·V Lopez-Majano, G Renzi
Aug 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·D L Hahn, R Golubjatnikov
Jul 10, 1991·JAMA : the Journal of the American Medical Association·D L HahnR Golubjatnikov
Aug 16, 1972·Nature: New Biology·E M LukanidinG P Georgiev
Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·C C KuoE P Benditt
Dec 1, 1994·International Journal of Epidemiology·M KarvonenP Saikku
Jan 1, 1994·Scandinavian Journal of Infectious Diseases·G FalckH Gnarpe
May 1, 1994·The Journal of Hand Surgery·S H Kozin, A T Bishop
Jan 1, 1993·Allergy·P Burney
Sep 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M R EkmanP Saikku

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Citations

Mar 25, 2004·Protein Expression and Purification·Xipeng Liu, Jianhua Liu
Mar 20, 2004·Pharmacology & Therapeutics·Philip M HansbroPeter G Gibson
Jan 6, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·David L Hahn, Rosanna W Peeling
Oct 29, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D L Hahn
Mar 17, 2000·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D L HahnP Saikku
Jun 3, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·N MiyashitaT Matsushima
Nov 11, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·D L Hahn, R McDonald
Apr 24, 2001·American Journal of Respiratory and Critical Care Medicine·M GencayM Roth
Jun 18, 2005·American Journal of Respiratory and Critical Care Medicine·Sebastian L Johnston, Richard J Martin
Jul 28, 2006·PLoS Clinical Trials·David L HahnGerald I Byrne
Dec 30, 2011·PloS One·Aino RantalaMaritta S Jaakkola
Aug 3, 2011·Annals of Indian Academy of Neurology·N K RaiM V Padma
Jun 9, 2012·Indian Journal of Pediatrics·Shally AwasthiJyotsna Agarwal
Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Mesut Gencay, Michael Roth
Mar 12, 2003·Chest·Robert F Lemanske
Dec 7, 2007·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Wudthichai SuttithawilRatanaporn Fuangtong
Jun 24, 2008·Journal of the Neurological Sciences·V C S S BandaruS Kaul
Jul 30, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P E Dahlberg, W W Busse
Jul 25, 2000·Clinics in Chest Medicine·M Kraft
Nov 17, 1998·Scandinavian Journal of Infectious Diseases·T AnttilaP Saikku
Jul 2, 2003·Journal of Comparative Pathology·D Longbottom, L J Coulter
Nov 18, 2005·Respiratory Medicine·Girolamo PelaiaSerafino A Marsico
Mar 1, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C. Mayaud, G. Mangiapan
Jun 27, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M P Foschino BarbaroG Miragliotta
Jul 13, 2016·Immunology and Allergy Clinics of North America·Tara F Carr, Monica Kraft
May 14, 2010·Current Opinion in Pharmacology·Rafael Firszt, Monica Kraft
Feb 9, 2008·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Ali KocabasSedat Kuleci
May 19, 2000·International Journal of Epidemiology·G D MillsM R Sears
Jul 8, 2000·Stroke; a Journal of Cerebral Circulation·M S ElkindR L Sacco
Apr 7, 1999·Nature Genetics·S KalmanR S Stephens
Jan 21, 2006·Stroke; a Journal of Cerebral Circulation·Mitchell S V ElkindMarco R Di Tullio
Jul 1, 2006·Treatments in Respiratory Medicine·Arne Simon, Oliver Schildgen
Aug 24, 2007·Acta Neurologica Scandinavica·B Piechowski-JóźwiakH Kwieciński
Jul 9, 1998·The Pediatric Infectious Disease Journal·E NormannB Wettergren
May 16, 2002·Current Opinion in Pediatrics·Michelle M Montalbano, Robert F Lemanske
May 10, 2005·Clinical and Diagnostic Laboratory Immunology·Mika PaldaniusPekka Saikku
Feb 28, 2021·Respiratory Research·Doriane CalmesFlorence Schleich
Jul 25, 2000·Microbial Pathogenesis·G S MyersK S Sriprakash

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