PMID: 9655039Jul 9, 1998Paper

Association of cutaneous and oral diseases in HIV-infected men

Oral Diseases
G W MirowskiJ S Greenspan

Abstract

Mucocutaneous diseases are common in patients infected with human immunodeficiency virus (HIV). To identify cutaneous diseases for which HIV-infected people are at high risk, we sought those that are strongly associated with specific HIV-related oral lesions and with progression of HIV disease. A cross-sectional study of HIV-positive outpatients referred to a university stomatology clinic for diagnosis and treatment of oral diseases. Each subject underwent both complete oral and cutaneous examinations. Among 55 men, with a median age of 41 years and a median CD4 cell count of 125/microliter (range 0-950/microliter), 93% had active oral diseases or conditions, including candidiasis, hairy leukoplakia, ulcers, Kaposi's sarcoma (KS), and xerostomia, and 95% had skin conditions, including onychomycosis, dermatophytosis, seborrheic dermatitis, KS, folliculitis, xerosis, and molluscum contagiosum. Seborrheic dermatitis, xerosis, skin KS, and molluscum contagiosum were associated with oral HIV-sentinel lesions (oral candidiasis, hairy leukoplakia, and KS), with low CD4 cell counts, and with AIDS. Our results suggest that xerosis and seborrheic dermatitis may be early harbingers of HIV disease progression. Their roles as predictors war...Continue Reading

References

Feb 1, 1990·Oral Surgery, Oral Medicine, and Oral Pathology·R BaroneF Mazzotta
Aug 1, 1987·Journal of the American Academy of Dermatology·D S GoodmanE Hershenbaum
Apr 1, 1997·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·H PalacioD Greenspan

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Citations

Mar 12, 2003·American Journal of Clinical Dermatology·Fiza Singh, Donald Rudikoff
Jun 29, 2004·International Dental Journal·A PinheiroP G Robinson
Nov 24, 1999·Oral Diseases·A BaquiW Falkler
May 11, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·V MargiottaV Abbadessa

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