Association of day 4 cumulative fluid balance with mortality in critically ill patients with influenza: A multicenter retrospective cohort study in Taiwan

PloS One
Wen-Cheng ChaoTSIRC (Taiwan Severe Influenza Research Consortium)

Abstract

Fluid balance is a fundamental management of patients with sepsis, and this study aimed to investigate the impact of cumulative fluid balance on critically ill patients with influenza admitted to an intensive care unit (ICU). This multicenter retrospective cohort study was conducted by the Taiwan Severe Influenza Research Consortium (TSIRC) which includes eight medical centers. Patients with virology-proven influenza infection admitted to ICUs between October 2015 and March 2016 were included for analysis. A total of 296 patients were enrolled (mean age: 61.4±15.6 years; 62.8% men), and 92.2% (273/296) of them required mechanical ventilation. In the survivors, the daily fluid balance was positive from day 1 to day 3, and then gradually became negative from day 4 to day 7, whereas daily fluid balance was continuously positive in the non-survivors. Using the cumulative fluid balance from day 1-4 as a cut-off point, we found that a negative cumulative day 1-4 fluid balance was associated with a lower 30-day mortality rate (log-rank test, P = 0.003). To evaluate the impact of shock on this association, we divided the patients into shock and non-shock groups. The positive correlation between negative day 1-4 fluid balance and mortal...Continue Reading

References

Jan 17, 2002·The New England Journal of Medicine·E RiversUNKNOWN Early Goal-Directed Therapy Collaborative Group
May 23, 2006·The New England Journal of Medicine·UNKNOWN National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials NetworkAndrea L Harabin
Oct 4, 2012·JAMA : the Journal of the American Medical Association·Stephen FröhlichJohn Boylan
Nov 1, 2013·The New England Journal of Medicine·Jean-Louis Vincent, Daniel De Backer
Mar 19, 2014·The New England Journal of Medicine·Donald M YealyDerek C Angus
Sep 11, 2014·British Journal of Anaesthesia·E A HosteUNKNOWN ADQI XII Investigators Group
Oct 2, 2014·The New England Journal of Medicine·Sandra L PeakePatricia Williams
Nov 25, 2014·Journal of Internal Medicine·S M Opal, T van der Poll
Dec 9, 2014·The American Journal of Emergency Medicine·Josep-Maria SirventCarolina Lorencio
Mar 18, 2015·The New England Journal of Medicine·Paul R MounceyUNKNOWN ProMISe Trial Investigators
Mar 21, 2015·The European Respiratory Journal·Susanne HeroldG R Scott Budinger
Apr 25, 2015·Revista Brasileira de terapia intensiva·Andrea Regina Lopes Cunha, Suzana Margareth Ajeje Lobo
Jun 16, 2015·Critical Care : the Official Journal of the Critical Care Forum·Angela Acheampong, Jean-Louis Vincent
Sep 26, 2015·Innate Immunity·Samira KhakpourJudith Hellman
Jan 8, 2016·Critical Care Medicine·Matthew W SemlerUNKNOWN National Institutes of Health National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Mervyn SingerDerek C Angus
Mar 18, 2016·Journal of Intensive Care·Tsuneo Tatara
Apr 9, 2016·Critical Care Medicine·Kelly Genga, James A Russell
Aug 25, 2016·The American Journal of Emergency Medicine·Evgeni BrotfainMoti Klein
Oct 5, 2016·BioMed Research International·Lukas MartinTobias Schuerholz
Nov 12, 2016·American Journal of Physiology. Lung Cellular and Molecular Physiology·Parker S WoodsIan C Davis
Aug 18, 2017·American Journal of Public Health·Danielle L MouliaSamuel B Graitcer
Nov 4, 2017·BMJ : British Medical Journal·Chris Del Mar, Peter Collignon

❮ Previous
Next ❯

Citations

Oct 9, 2019·Dimensions of Critical Care Nursing : DCCN·Jessica GomesFilipe Utuari de Andrade Coelho
Sep 2, 2020·Cancer Control : Journal of the Moffitt Cancer Center·Yung-Chun ChenWen-Cheng Chao
Apr 10, 2019·Critical Care : the Official Journal of the Critical Care Forum·Zhongheng ZhangYucai Hong
Feb 29, 2020·Annals of Intensive Care·Ming-Ju TsaiUNKNOWN for Taiwan Severe Influenza Research Consortium (TSIRC) Investigators

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.