Association of depressive symptom severity with coronary artery calcium: The Dallas heart study.

Journal of Affective Disorders
Amber KhanE Sherwood Brown

Abstract

Previous studies have yielded mixed results regarding the relationship between depressive symptoms and coronary artery calcium (CAC). This analysis sought to evaluate this relationship using a multiethnic, population-based cohort. Data were extracted from the second phase of the Dallas Heart Study (DHS-2). Depressive symptom severity was measured with the 16-item Quick Inventory of Depressive Symptomatology-Self Report (QIDS), a validated depressive symptom severity scale. A regression analysis was performed using QIDS score as the predictor variable and CAC as the outcome variable. Covariates included age, sex, ethnicity, diabetes, hypertension, smoking, systolic blood pressure, total cholesterol, HDL cholesterol, and body mass index. The cohort consisted of 2,293 individuals with a mean age of 50 years and included 47.1% female and 47.1% black participants. The mean QIDS score was 4.37(±3.69), and 43.3% had CAC > 0. Regression results indicated that QIDS does not statistically significantly predict whether one does or does not have CAC, when controlling for age, sex, and ethnicity (β = 0.088, p = .240, OR = 1.092, 95% CI 0.943-1.264). Cross sectional design is limited to one point in time, very depressed patients with higher ...Continue Reading

References

Jan 14, 1999·The New England Journal of Medicine·R Ross
Nov 4, 2000·The New England Journal of Medicine·P G O'MalleyA J Taylor
Mar 9, 2002·Arteriosclerosis, Thrombosis, and Vascular Biology·Anne B NewmanLewis H Kuller
Apr 7, 2004·Archives of General Psychiatry·Henning TiemeierMonique M B Breteler
Jun 15, 2004·The American Journal of Cardiology·Ronald G VictorUNKNOWN Dallas Heart Study Investigators
Jun 7, 2006·Annals of Internal Medicine·Ana V Diez RouxColin Wu
Oct 3, 2006·Psychosomatic Medicine·Karen MatthewsTeresa Seeman
Mar 28, 2008·The New England Journal of Medicine·Robert DetranoRichard A Kronmal
Jun 4, 2008·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·E Sherwood BrownA John Rush
Nov 4, 2008·Annals of Medicine·Johnny Nijm, Lena Jonasson
Feb 4, 2009·Psychosomatic Medicine·M Bryant HowrenJerry Suls
Apr 22, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Patricia A ZunszainCarmine M Pariante
Oct 16, 2010·Journal of the American College of Cardiology·Raimund ErbelUNKNOWN Heinz Nixdorf Recall Study Investigative Group
Oct 28, 2010·Psychosomatic Medicine·Alan RozanskiDaniel S Berman
Dec 26, 2012·JAMA Psychiatry·Marie Kim Wium-AndersenBørge Grønne Nordestgaard
Jul 23, 2013·Journal of Affective Disorders·Vyara ValkanovaCharlotte L Allan
May 4, 2016·The American Journal of Cardiology·Imke JanssenSusan A Everson-Rose
May 30, 2016·The American Journal of Cardiology·Itamar S SantosIsabela M Bensenor
Nov 18, 2016·Nature Reviews. Cardiology·Robert M Carney, Kenneth E Freedland
Jul 25, 2017·Journal of Cardiovascular Computed Tomography·Andre R M PaixaoAmit Khera
Feb 2, 2018·Circulation·Emelia J BenjaminUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Nov 20, 2020·The Journal of Clinical Psychiatry·Samara HuckvaleE Sherwood Brown

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