Association of Digital Breast Tomosynthesis vs Digital Mammography With Cancer Detection and Recall Rates by Age and Breast Density

JAMA Oncology
E F ConantPopulation-based Research Optimizing Screening Through Personalized Regimen (PROSPR) Consortium

Abstract

Breast cancer screening examinations using digital breast tomosynthesis (DBT) has been shown to be associated with decreased false-positive test results and increased breast cancer detection compared with digital mammography (DM). Little is known regarding the size and stage of breast cancer types detected and their association with age and breast density. To determine whether screening examinations using DBT detect breast cancers that are associated with an improved prognosis and to compare the detection rates by patient age and breast density. This retrospective analysis of prospective cohort data from 3 research centers in the Population-based Research Optimizing Screening Through Personalized Regimens (PROSPR) consortium included data of women aged 40 to 74 years who underwent screening examinations using DM and DBT from January 1, 2011, through September 30, 2014. Statistical analysis was performed from November 8, 2017, to August 14, 2018. Use of DBT as a supplement to DM at breast cancer screening examination. Recall rate, cancer detection rate, positive predictive value, biopsy rate, and distribution of invasive cancer subtypes. Among 96 269 women (mean [SD] patient age for all examinations, 55.9 [9.0] years), patient a...Continue Reading

References

May 25, 2013·AJR. American Journal of Roentgenology·Stephen L RoseRussell Sexton
Jul 25, 2014·JAMA : the Journal of the American Medical Association·Sarah M FriedewaldEmily F Conant
Sep 5, 2014·Radiology·Melissa A DurandLiane E Philpotts
Oct 15, 2014·Journal of the National Cancer Institute·Anne Marie McCarthyEmily F Conant
Oct 27, 2015·AJR. American Journal of Roentgenology·Elizabeth S McDonaldEmily F Conant
Feb 20, 2016·JAMA Oncology·Nehmat Houssami, Diana L Miglioretti
May 20, 2017·Breast Cancer Research and Treatment·Elizabeth A RaffertyLoren T Niklason
Aug 24, 2017·AJR. American Journal of Roentgenology·Jin You KimKi Seok Choo
Jan 11, 2018·JAMA : the Journal of the American Medical Association·Sylvia K PlevritisJeanne S Mandelblatt
Jan 13, 2018·The Breast : Official Journal of the European Society of Mastology·Nehmat HoussamiPetra Macaskill
Mar 21, 2018·Radiology·Etta D Pisano
May 26, 2018·JAMA Oncology·Anne Marie McCarthyUNKNOWN PROSPR Consortium
Aug 15, 2018·Journal of the National Cancer Institute·M Luke MarinovichNehmat Houssami

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Citations

Sep 11, 2019·Journal of the National Cancer Institute·Kathryn P LowryNatasha K Stout
Nov 14, 2019·Physics in Medicine and Biology·Hui SunShanshan Wang
Jul 29, 2020·JAMA Network Open·Catherine M TuiteLori J Goldstein
Sep 10, 2020·AJR. American Journal of Roentgenology·Wendie A BergHabib Rahbar
Sep 26, 2020·Insights Into Imaging·Rubina Manuela TrimboliFrancesco Sardanelli
Aug 16, 2019·Radiology·Michael H Fuchsjäger, Gabriel Adelsmayr
Jul 25, 2020·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Habib RahbarChristoph I Lee
Jun 20, 2020·AJR. American Journal of Roentgenology·Elizabeth H DibbleMichael K O'Connor
Sep 9, 2020·Radiology·Ritse M MannLinda Moy
Jul 19, 2019·BMJ : British Medical Journal·Jeanne Lenzer
Jul 30, 2020·Journal of Women's Health·Suneela VeguntaBhavika K Patel
May 30, 2020·Journal of General Internal Medicine·Lydia E Pace
Sep 21, 2019·The British Journal of Radiology·Almir Gv BitencourtElizabeth A Morris
Dec 19, 2020·Journal of Medical Screening·Tali AmirLisa A Mullen
Nov 17, 2020·Clinical Imaging·Kathryn ZamoraBrittany Hermecz
Feb 6, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Yiming GaoSamantha L Heller
Feb 17, 2021·Academic Radiology·Stamatia DestounisAmanda Santacroce
Feb 20, 2021·Journal of the American College of Radiology : JACR·Nila AlsheikEmily Conant
Apr 4, 2021·International Journal of Molecular Sciences·Braden MillerLacey R McNally
Apr 7, 2021·Journal of the National Cancer Institute·Ilana B RichmanCary P Gross
Jul 20, 2021·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Jean Morag SeelyWendie A Berg

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