Association of fatty acids in serum phospholipids with lung function and bronchial hyperresponsiveness in adults.

European Journal of Epidemiology
Iris KompauerJoachim Heinrich

Abstract

The dietary intake of certain fatty acids might have an impact on inflammatory processes in the lung and therefore contribute to the development of lung diseases like asthma or COPD. In this study data from a population based cross-sectional study on respiratory health including measurement of fatty acids in serum phospholipids of 593 adults between 20 and 64 years of age were analyzed. Statistically significant positive associations were found between percentage predicted FEV1 (P = 0.0085) and FVC (P = 0.0267) and docosahexaenoic acid concentration in serum phospholipids in men. Dihomo-gamma-linolenic acid content in serum phospholipids was significantly negatively associated with percentage predicted FEV1 (P = 0.0003) and FVC (P = 0.0045) and transformed dose-response slopes (P = 0.0488) in men. Palmitoleic acid was negatively associated with percentage predicted FEV1 (P = 0.0037) and FVC (P = 0.0029) in men. Other fatty acids in serum phospholipids did not consistently affect lung function parameters or bronchial hyperreactivity. A high concentration of docosahexaenoic acid in serum phospholipids may have a protective effect on lung function. Because this long-chain n-3 polyunsaturated fatty acid is almost exclusively derive...Continue Reading

References

Mar 1, 1988·Clinical Allergy·C M KirschW M Gold
Jul 1, 1986·Analytical Biochemistry·L Kolarovic, N C Fournier
May 1, 1995·American Journal of Respiratory and Critical Care Medicine·R J TroisiF E Speizer
May 1, 1994·The European Respiratory Journal·P G BurneyD Jarvis
Dec 31, 1997·American Journal of Respiratory and Critical Care Medicine·B LeynaertF Neukirch
Jan 13, 1998·The European Respiratory Journal·S ChinnC Luczynska
Sep 4, 1998·The European Respiratory Journal·O FlugeA Gulsvik
Feb 9, 1999·The Journal of Allergy and Clinical Immunology·P N Black
Jun 3, 1999·American Journal of Respiratory and Critical Care Medicine·E ShaharJ H Eckfeldt
Sep 10, 1999·Annals of Medicine·P KankaanpääE Isolauri
Nov 24, 1999·Thorax·M R Becklake, F Kauffmann
Jan 5, 2000·The American Journal of Clinical Nutrition·J Schwartz
May 24, 2000·European Journal of Clinical Nutrition·A Zeleniuch-JacquotteP Toniolo
Feb 13, 2001·Allergy·G BalzanoS Bonini
Feb 17, 2001·American Journal of Respiratory and Critical Care Medicine·C L CarlsonUNKNOWN Cardiovascular Health Study Research Group
Mar 4, 2003·The Journal of Nutrition·Lenore Arab
Aug 20, 2003·Respiratory Medicine·Judith E MuellerJoachim Heinrich
Aug 26, 2003·The American Journal of Clinical Nutrition·Rosalie K WoodsMichael J Abramson
Feb 5, 2004·Thorax·R K WoodsF C K Thien
Mar 31, 2004·The American Journal of Clinical Nutrition·Samantha KewParveen Yaqoob
Apr 16, 2004·The European Respiratory Journal·M A Trak-FellermeierJ Heinrich
Aug 10, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E C BroadfieldA Fogarty
Aug 27, 2004·European Journal of Clinical Nutrition·G Nagel, J Linseisen
Jan 1, 2005·Pharmacology & Therapeutics·Charles N Serhan
Jan 7, 2005·Journal of the American Dietetic Association·Ka W Wong
Feb 18, 2005·Current Opinion in Clinical Nutrition and Metabolic Care·Charles N Serhan

❮ Previous
Next ❯

Citations

Dec 15, 2010·European Journal of Epidemiology·Albert Hofman
Apr 24, 2010·Respiratory Research·Eva SchnabelUNKNOWN KORA (Cooperative Research in the Region of Augsburg) study group
Aug 1, 2013·Lipids in Health and Disease·Tatyana P NovgorodtsevaTatyana A Gvozdenko
Aug 31, 2011·European Journal of Epidemiology·Albert HofmanJacqueline C M Witteman
Sep 4, 2009·European Journal of Epidemiology·Albert HofmanJacqueline C M Witteman
Oct 23, 2010·European Journal of Epidemiology·Vincent W V JaddoeAlbert Hofman
Nov 11, 2008·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Oswald QuehenbergerEdward A Dennis
Jan 1, 2014·Respirology : Official Journal of the Asian Pacific Society of Respirology·Eric L A Fonseca WaldAnnemie M W J Schols
May 18, 2013·Respiratory Medicine·Marie WaatevikAne Johannessen
Jan 13, 2015·Allergology International : Official Journal of the Japanese Society of Allergology·Jun Miyata, Makoto Arita
Mar 13, 2014·The Journal of Allergy and Clinical Immunology·Stacy Gelhaus WendellFernando Holguin
Apr 19, 2016·Nutrition Research and Practice·Eunyu Cho, Yongsoon Park
Dec 27, 2018·International Journal of Environmental Research and Public Health·Shahieda AdamsMohamed F Jeebhay
Feb 10, 2009·European Journal of Epidemiology·Thomas Behrens
Sep 11, 2018·American Journal of Respiratory and Critical Care Medicine·Jiayi XuDana B Hancock
Sep 13, 2012·Journal of Korean Medical Science·Dong-Hun HanJin-Bom Kim
Dec 11, 2019·Nutrients·Urszula RadzikowskaMilena Sokolowska
Aug 30, 2019·Lung India : Official Organ of Indian Chest Society·Ümüş ÖzbeyAliye Gamze Calis
Mar 26, 2019·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Toni A M TobiasDeepa Rastogi
Jul 23, 2020·Medicine and Science in Sports and Exercise·Rongsong LiHarry B Rossiter
Sep 4, 2021·The American Journal of Clinical Nutrition·Carmen Marín-HinojosaJose Luis Lopez-Campos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.