Association of Fecundity With Changes in Adult Female Weight

Obstetrics and Gynecology
Audrey J GaskinsJorge E Chavarro

Abstract

To evaluate whether weight change since age 18 years, current body mass index (BMI), and BMI at age 18 years are associated with fecundity. Our study included 1,950 women in the Nurses' Health Study 3 (2010-2014), a prospective cohort study, currently attempting pregnancy. Height, current weight, and weight at age 18 years were self-reported on the baseline questionnaire. Every 3-6 months thereafter, women reported the current duration of their pregnancy attempt. Multivariable-accelerated failure time models were used to estimate the time ratios and 95% confidence intervals (CIs). For every 5-kg increase in body weight from age 18 years, current duration of pregnancy attempt increased by 5% (95% CI 3-7%). Compared with women who maintained weight, the adjusted median current duration was 0.5 months shorter in those who lost weight, 0.3 months longer for those who gained 4-9.9 kg and 10-19.9 kg, and 1.4 months longer for those who gained 20 kg or more (P trend ≤.001). The adjusted time ratio (95% CI) for a 5-kg/m increase in current BMI was 1.08 (1.04-1.12). After multivariable adjustment (including adjustment for current BMI), being underweight at age 18 years (BMI less than 18.5) was associated with a longer current duration o...Continue Reading

References

Apr 1, 1995·Public Health Nursing·E E Gulick, L Escobar-Florez
Jul 1, 1994·American Journal of Obstetrics and Gynecology·J W Rich-EdwardsJ E Manson
Jul 1, 1993·Fertility and Sterility·M JoffeM Vessey
Jun 29, 2000·American Journal of Epidemiology·F BolúmarL Bisanti
Jun 7, 2006·Epidemiology·Rémy SlamaJean Bouyer
Nov 11, 2006·Human Reproduction·D C Gesink LawM P Longnecker
Mar 9, 2007·Human Reproduction·C H Ramlau-HansenJ Olsen
Jul 13, 2007·Current Opinion in Obstetrics & Gynecology·Scott M Nelson, Richard Fleming
Aug 19, 2007·Epidemiology·Markus JokelaLiisa Keltikangas-Järvinen
Oct 10, 2008·The American Journal of Clinical Nutrition·Markus JokelaMika Kivimäki
Dec 6, 2008·Epidemiology·Maureen A CooneyCourtney D Lynch
Oct 16, 2009·Human Reproduction·Lauren A WiseElizabeth E Hatch
Jun 1, 2011·Journal of Assisted Reproduction and Genetics·Scott H Purcell, Kelle H Moley
Jul 7, 2011·Proceedings of the National Academy of Sciences of the United States of America·Kaisa SelesniemiJonathan L Tilly
Dec 18, 2012·Human Reproduction Update·N SermondadeS Czernichow
Oct 30, 2013·Nutrition Reviews·Emily S JungheimMargaret M Hopeman
Jul 19, 2014·Annals of Epidemiology·Larissa R Brunner HuberDelia Scholes
Aug 19, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K A SimA Sainsbury
Sep 10, 2014·Obstetrics and Gynecology·Audrey J GaskinsJorge E Chavarro

❮ Previous
Next ❯

Citations

Apr 30, 2016·Fertility and Sterility·Craig J McKinnonLauren A Wise
Jul 3, 2018·Panminerva Medica·Majdi ImteratAvi Harlev
Feb 9, 2019·BJOG : an International Journal of Obstetrics and Gynaecology·J A GriegerC T Roberts
Dec 24, 2015·Obstetrics and Gynecology·Shunjie ChuaPeter Lemark
Dec 24, 2015·Obstetrics and Gynecology·Audrey J GaskinsJorge E Chavarro
Oct 27, 2018·Revista da Associação Médica Brasileira·José Maria Soares JúniorEdmund C Baracat
May 8, 2018·Human Reproduction·Jessica A GriegerClaire T Roberts
Feb 6, 2021·Frontiers in Endocrinology·Andrea GarollaCarlo Foresta
Jan 14, 2021·The Journal of Nutrition·Audrey J GaskinsUNKNOWN EARTH Study Team
Jul 24, 2021·Evolutionary Applications·Natalie L Dinsdale, Bernard J Crespi
Jul 14, 2021·Biological Reviews of the Cambridge Philosophical Society·Bogusław Pawłowski, Agnieszka Żelaźniewicz
Aug 28, 2021·Reproductive Biomedicine Online·Gemma FabozziFilippo Maria Ubaldi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Occupational and Environmental Medicine
Audrey J GaskinsJorge E Chavarro
Journal of Neuro-oncology
Erin M SiegelKathleen M Egan
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Bianca YuhAmy C Justice
© 2021 Meta ULC. All rights reserved