Association of fitness and body fatness with left ventricular mass: The Heart Health Study.

Obesity Science & Practice
Renee J RogersJohn M Jakicic

Abstract

Left ventricular mass (LVM) is a clinical prognostic indicator of cardiovascular disease. Left ventricular mass is associated with body size (body mass index [BMI], weight, and body surface area [BSA]). This study examined if the association between body size (weight, BMI, and BSA) and LVM is influenced by body composition and cardiorespiratory fitness in adults who are overweight or obese. This study included cross-sectional baseline data from a randomized clinical trial. Participants included 379 adults (age, 45.6 ± 7.9 y) who were overweight or obese (BMI, 32.4 ± 3.8 kg·m-2). Measures included weight, height, BMI, BSA, body composition, cardiorespiratory fitness, and LVM by cardiac magnetic resonance imaging (CMR). Left ventricular mass was positively associated with weight, BMI, BSA, and fitness (P < .0001) and inversely associated with percent body fat (P < .0001). Stepwise multiple regression models showed that body fatness was inversely associated and cardiorespiratory fitness was positively associated with LVM even after considering weight, BMI, or BSA in the analyses. These cross-sectional findings support that in adults who are overweight or obese but otherwise relatively healthy, LVM is associated with both body comp...Continue Reading

References

Mar 6, 1986·The New England Journal of Medicine·R S PaffenbargerC C Hsieh
Jan 1, 1993·Medicine and Science in Sports and Exercise·R S PaffenbargerR T Hyde
Feb 25, 1993·The New England Journal of Medicine·R S PaffenbargerJ B Kampert
Mar 13, 1999·The American Journal of Clinical Nutrition·C D LeeA S Jackson
Mar 23, 2001·JAMA : the Journal of the American Medical Association·I M LeeJ E Buring
Jun 11, 2002·Obesity Research·Stephen W FarrellSteven N Blair
Aug 18, 2004·Journal of the American College of Cardiology·Gillian A WhalleyJames C Baldi
Nov 30, 2007·Medicine and Science in Sports and Exercise·Rena R WingUNKNOWN LOOK AHEAD RESEARCH GROUP
Oct 31, 2008·British Journal of Sports Medicine·D C LeeS N Blair
Mar 13, 2010·JACC. Cardiovascular Imaging·Evrim B TurkbeyDavid A Bluemke
Jul 2, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Samuel S GiddingJulius Gardin
Oct 16, 2013·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·James C MoonUNKNOWN Cardiovascular Magnetic Resonance Working Group of the European Society of Cardiology
Jan 18, 2014·American Journal of Public Health·Luisa N Borrell, Lalitha Samuel
Jan 21, 2014·Progress in Cardiovascular Diseases·Marjorie BastienJean-Pierre Després
Jan 23, 2016·Journal of the American College of Cardiology·James C MoonErik B Schelbert
Sep 23, 2016·JAMA : the Journal of the American Medical Association·John M JakicicSteven H Belle
May 18, 2017·Circulation. Cardiovascular Imaging·Erik B SchelbertMihai Gheorghiade

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May 1, 2020·Psychophysiology·Sarah L AghjayanKirk I Erickson

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