Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample

Behavior Genetics
Arpana AgrawalDanielle M Dick

Abstract

Results from twin studies suggest that overlapping genetic factors influence alcohol dependence and illicit drug dependence. Using data from the Collaborative Study on the Genetics of Alcoholism (COGA), we examined the association between 69 SNPs in the GABAA receptor gene cluster on chromosome 4 and marijuana and illicit drug dependence, individually, and as co-occurring phenotypes with alcohol dependence. Results suggested association between marijuana dependence and illicit drug dependence with SNPs in the GABRA2 gene. Interestingly, the evidence for association previously observed with alcohol dependence came only from individuals with comorbid illicit drug dependence. There was no association with other genes in the GABAA cluster on chromosome 4 with illicit drug dependence.

References

Feb 1, 1992·Journal of Abnormal Psychology·M McGueD S Svikis
Jan 1, 1991·Comprehensive Psychiatry·S M MirinJ L Michael
Oct 1, 1988·The International Journal of the Addictions·W H MellerE Troughton
Jun 1, 1993·American Journal of Public Health·D Kandel, K Yamaguchi
Aug 1, 1995·Drug and Alcohol Dependence·R W PickensM C LaBuda
May 29, 1998·American Journal of Medical Genetics·T ReichH Begleiter
Aug 12, 1998·The American Journal of Psychiatry·K S Kendler, C A Prescott
Nov 18, 1998·Archives of General Psychiatry·K R MerikangasB J Rounsaville
Dec 5, 1998·Drug and Alcohol Dependence·M B van den BreeR W Pickens
Feb 2, 1999·The British Journal of Psychiatry : the Journal of Mental Science·K S Kendler, C A Prescott
Jul 1, 1993·Journal of Mental Health Administration·M Argeriou, D McCarty
Jun 16, 1999·Journal of Consulting and Clinical Psychology·M McGueW G Iacono
Jan 1, 2000·Addiction·M HesselbrockV Hesselbrock
May 2, 2000·The British Journal of Psychiatry : the Journal of Mental Science·K S KendlerM C Neale
May 29, 2000·American Journal of Human Genetics·E R MartinN L Kaplan
Aug 3, 2000·Alcoholism, Clinical and Experimental Research·T ForoudT Reich
Oct 31, 2000·American Journal of Medical Genetics·N L SacconeJ P Rice
Oct 31, 2000·American Journal of Medical Genetics·L M KarkowskiK S Kendler
Oct 31, 2000·American Journal of Medical Genetics·M McGueW G Iacono
Feb 15, 2001·Drug and Alcohol Dependence·D R MilesR W Pickens
Mar 20, 2001·American Journal of Human Genetics·E R MartinN L Kaplan
Oct 19, 2002·Biological Psychology·Bernice PorjeszTheodore Reich
Aug 14, 2003·Genetic Epidemiology·Frank Dudbridge
Dec 10, 2003·Archives of General Psychiatry·Soo Hyun RheeMichael C Stallings
Jul 27, 2004·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Jonathan CovaultHenry R Kranzler
Mar 17, 2005·The American Journal of Drug and Alcohol Abuse·Matthew L HillerMichele Staton
Apr 19, 2005·Alcoholism, Clinical and Experimental Research·Jaakko LappalainenJoel Gelernter

❮ Previous
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Citations

Nov 4, 2011·Human Genetics·Wen-Yan CuiMing D Li
Dec 13, 2006·Behavior Genetics·Danielle M DickLaura Bierut
Aug 15, 2013·Behavior Genetics·Matt McGueWilliam G Iacono
Mar 17, 2006·Current Psychiatry Reports·Danielle M Dick, Laura J Bierut
Jan 22, 2011·Current Psychiatry Reports·Jens Treutlein, Marcella Rietschel
Apr 9, 2013·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Danielle M DickJohn Kramer
Jan 28, 2012·Nature Neuroscience·Kenneth S KendlerBrien Riley
Sep 27, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Mary-Anne EnochDavid Goldman
Jul 30, 2011·Nature Reviews. Drug Discovery·Uwe Rudolph, Frédéric Knoflach
May 29, 2013·Nature Reviews. Gastroenterology & Hepatology·Howard J Edenberg, Tatiana Foroud
May 18, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Jonathan CovaultHenry R Kranzler
Jul 19, 2012·Translational Psychiatry·A AgrawalM T Lynskey
Aug 13, 2009·Psychiatric Genetics·Robert A PhilibertWilliam Adams
Feb 22, 2012·Genome Biology·Tatiana V MorozovaRobert R H Anholt
Mar 26, 2008·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Penelope A LindJohn B Whitfield
Dec 11, 2013·European Psychiatry : the Journal of the Association of European Psychiatrists·N CarmiolD C Glahn
Jan 8, 2014·Molecular Genetics and Genomics : MGG·Tatiana V MorozovaRobert R H Anholt
Nov 28, 2013·Nature Communications·Quentin M AnsteeHoward C Thomas
Oct 5, 2013·Current Psychiatry Reports·Mary-Anne Enoch
Mar 26, 2015·European Child & Adolescent Psychiatry·Frances L WangKathryn Lemery-Chalfant
Oct 23, 2010·Behavioural Brain Research·Isabel VollenweiderUwe Rudolph
Sep 14, 2010·Clinics in Laboratory Medicine·Sarah M Hartz, Laura J Bierut
Feb 18, 2010·The Psychiatric Clinics of North America·Sarah M Hartz, Laura J Bierut
Apr 29, 2008·Pharmacology, Biochemistry, and Behavior·Mary-Anne Enoch
Nov 30, 2006·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Madhavi RangaswamyHenri Begleiter
May 12, 2009·Alcoholism, Clinical and Experimental Research·Lara A Ray, Kent E Hutchison
Nov 27, 2008·Addiction·Arpana AgrawalPamela A F Madden
Apr 2, 2009·Addiction·Arpana Agrawal, Michael T Lynskey
Aug 30, 2008·Alcoholism, Clinical and Experimental Research·Penelope A LindJohn B Whitfield
Oct 3, 2008·Alcoholism, Clinical and Experimental Research·Bao-Zhu YangJoel Gelernter
May 23, 2008·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Kristen C JacobsonUNKNOWN Participants in the Collaborative Study on the Genetics of Alcoholism

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