Abstract
Twin pregnancies account for 3% of live births but experience substantially more perinatal morbidity and mortality than singleton pregnancies. Optimizing the timing of birth is a key strategy in improving twin pregnancy outcomes. Current UK and US policies are based on observational studies of perinatal mortality and not on longer-term effects. The association of timing of birth with long-term childhood outcomes among twins is uncertain. To identify the optimal gestation week for birth of twin infants by calculating the week of birth associated with the lowest risk of short-term and long-term adverse outcomes (perinatal mortality and special educational need [SEN] at school). This population-based, data-linkage cohort study included 43 133 twin infants born at a gestational age of 34 weeks onward between January 1, 1980, and December 31, 2015, in Scotland. The data were analyzed from June 1, 2017, to March 1, 2019. Gestational age (in weeks) at the time of birth. The primary outcomes were extended perinatal mortality and a record of SEN (≥1 of intellectual disabilities, dyslexia, physical or motor impairment, language or speech disorder, autistic spectrum disorder, and social, emotional, or behavioral difficulties) at school (c...Continue Reading
References
May 8, 1996·JAMA : the Journal of the American Medical Association·H Minakami, I Sato
Jan 12, 2000·Gynecologic and Obstetric Investigation·S SuzukiT Araki
Nov 2, 2002·BMJ : British Medical Journal·Gordon C S SmithRichard Dobbie
Oct 11, 2003·Obstetrics and Gynecology·Bronwen KahnJulian N Robinson
Jan 27, 2004·BMJ : British Medical Journal·Frans M HelmerhorstMarc J N C Keirse
Jan 27, 2005·American Journal of Obstetrics and Gynecology·Gordon C S Smith
Sep 7, 2007·Pediatric Research·Martha G EideTor Bjerkedal
Apr 22, 2009·Archives of Gynecology and Obstetrics·Shunji Suzuki, Hidehiko Miyake
Jun 9, 2009·Pediatric Clinics of North America·Bonnie E Stephens, Betty R Vohr
Jun 15, 2010·PLoS Medicine·Daniel F MacKayJill P Pell
Oct 1, 2010·Optometry : Journal of the American Optometric Association
Jul 22, 2011·Obstetrics and Gynecology·Catherine Y SpongGeorge Saade
Oct 1, 2011·BMJ : British Medical Journal·Cristina VisintinUNKNOWN Guideline Development Group
May 12, 2012·BMJ : British Medical Journal·Sarah J StockJane E Norman
Feb 22, 2013·BMJ : British Medical Journal·Ella FieldsUNKNOWN Guideline Development Group
May 3, 2014·Obstetrics and Gynecology
Jul 28, 2015·JAMA Pediatrics·Wade Harrison, David Goodman
Sep 8, 2016·BMJ : British Medical Journal·Fiona Cheong-SeeUNKNOWN Global Obstetrics Network (GONet) Collaboration
Nov 20, 2016·BJOG : an International Journal of Obstetrics and Gynaecology
Nov 15, 2017·PLoS Medicine·Hannah E KnightGordon C S Smith
Mar 1, 2019·American Journal of Obstetrics and Gynecology·William A Grobman, Aaron B Caughey