Association of Giant Cell Arteritis With Race.

JAMA Ophthalmology
Anna M GruenerTimothy J McCulley

Abstract

Giant cell arteritis (GCA) is the most common vasculitis in adults and is associated with significant morbidity and mortality. Its incidence has been carefully studied in white populations, yet its relevance among other racial and ethnic groups is less well known. To examine the incidence of biopsy-proven GCA (BP-GCA) in a tertiary care center-based population with a sizeable proportion of black patients. This retrospective cohort study identified all patients who underwent temporal artery biopsy (TAB) from July 1, 2007, through September 30, 2017, using the electronic medical record system at the Johns Hopkins Wilmer Eye Institute. Associations between self-reported race, sex, and age were explored and compared with all other patients attending the hospital over the same period. Data were analyzed from November 1, 2017, through July 31, 2018. Estimated incidence rates of BP-GCA in black and white patients. Among 586 patients who underwent TAB (mean [SD] age, 70.5 [11.1] years; age range, 32-103 years; 423 [72.2%] women), 167 (28.5%) were black, 382 (65.2%) were white, and 37 (6.3%) were other or unknown. Of 573 individuals 50 years and older, 92 (16.1%) had BP-GCA; 14 were black (8.4% of all black patients undergoing testing) ...Continue Reading

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Jan 20, 2021·Circulation·David SaadounPatrice Cacoub
Mar 16, 2021·Frontiers in Immunology·Michelle L RobinettePaul A Monach
Sep 29, 2020·Rheumatic Diseases Clinics of North America·Jessica N WilliamsCandace H Feldman

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