Association of Hydrocodone Schedule Change With Opioid Prescriptions Following Surgery

JAMA Surgery
Joe HabboucheJennifer F Waljee

Abstract

In 2014, the US Drug Enforcement Administration moved hydrocodone-containing analgesics from schedule III to the more restrictive schedule II to limit prescribing and decrease nonmedical opioid use. The association of this policy change with postoperative prescribing is not well understood. To examine the hypothesis that the amount of opioids prescribed following surgery is associated with the rescheduling of hydrocodone. An interrupted time series analysis of outpatient opioid prescriptions was conducted to examine the trends in the amount of postoperative opioids filled before and after the schedule change. Opioid prescriptions filled between January 2012 and October 2015 were analyzed using insurance claims data from the Michigan Value Collaborative, which includes data from 75 hospitals across Michigan. A total of 21 955 adult inpatients 18 to 64 years of age who underwent 1 of 19 common elective surgical procedures and filled an opioid prescription within 14 days of discharge to home were eligible for inclusion. The primary outcome was the trends in the mean amount of opioids filled in oral morphine equivalents (OMEs) for the initial postoperative prescriptions before and after the schedule change date of October 6, 2014, ...Continue Reading

References

Jan 10, 1980·The New England Journal of Medicine·J Porter, H Jick
Feb 17, 2009·The American Journal on Addictions·Jon StreltzerUNKNOWN American Academy of Addiction Psychiatry
Mar 14, 2012·Archives of Internal Medicine·Asim AlamChaim M Bell
Apr 5, 2012·JAMA : the Journal of the American Medical Association·Aleksandra ZgierskaDavid Rabago
Feb 13, 2014·BMJ : British Medical Journal·Hance ClarkeDuminda N Wijeysundera
Jan 15, 2015·The New England Journal of Medicine·Richard C DartJody L Green
Sep 12, 2015·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Martin D Cheatle
Nov 17, 2015·PM & R : the Journal of Injury, Function, and Rehabilitation·Lynn R Webster, Martin Grabois
Jan 14, 2016·The New England Journal of Medicine·Wilson M ComptonGrant T Baldwin
Mar 16, 2016·JAMA : the Journal of the American Medical Association·Deborah DowellRoger Chou
Jul 19, 2016·Annals of Surgery·Jennifer F WaljeeMichael J Englesbe
Oct 1, 2016·Journal of Clinical Anesthesia·Kamal MaheshwariAndrea Kurz
Jan 10, 2017·Annals of Surgery·Atul A Gawande
Apr 14, 2017·JAMA Surgery·Chad M BrummettBrahmajee K Nallamothu
May 17, 2017·JAMA : the Journal of the American Medical Association·Jay S LeeJennifer F Waljee
Jun 9, 2017·Obstetrics and Gynecology·Brian T BatemanLisa R Leffert
Jul 12, 2017·Annals of Surgery·Cornelius A ThielsElizabeth B Habermann
Aug 3, 2017·JAMA Surgery·Mark C BicketChristopher L Wu

❮ Previous
Next ❯

Citations

Sep 4, 2019·Annals of Surgery·Ryan HowardJennifer Waljee
Feb 28, 2020·Journal of Dental Education·Shenam TickuHawazin W Elani
May 28, 2020·The Journal of Trauma and Acute Care Surgery·John A HarvinLillian S Kao
Oct 18, 2018·Frontiers in Pharmacology·Luigi CardiaEpifanio Mondello
Feb 7, 2021·Annals of Vascular Surgery·Mark D BalceniukMichael C Stoner
Jan 22, 2021·The International Journal on Drug Policy·Jonathan P CaulkinsMichael Rath
Nov 1, 2020·Journal of the American Pharmacists Association : JAPhA·Silken A UsmaniScott Martin Vouri
Feb 17, 2021·The Journal of the American Academy of Orthopaedic Surgeons·Chukwuweike U GwamJohannes F Plate
Oct 7, 2020·Pain·Corinne WoodsGerald Dal Pan
Apr 9, 2021·Peptides·Richard J Bodnar
Aug 2, 2021·Urology·Joel J WackerbarthSarah F Faris

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved