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Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy

Journal of Alzheimer's Disease : JAD

Jan 14, 2020

Chenjia XuSujuan Gao

Abstract

Animal studies have shown that diet-induced hypercholesterolemia (HC) increases amyloid-β (Aβ) accumulation and accelerates Alzheimer's disease (AD) pathology. However, the association of HC with AD in human studies has not been consistently established. We aimed to investigate the rela...read more

Mentioned in this Paper

Plaque (Lesion)
Neuron Projection Morphogenesis
Cerebral Amyloid Angiopathy
Human Study
Alzheimer's Disease
APOE gene
Analysis
Diet
Autopsy
Neuropathology
1
Paper Details
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Association of Hypercholesterolemia with Alzheimer's Disease Pathology and Cerebral Amyloid Angiopathy

Journal of Alzheimer's Disease : JAD

Jan 14, 2020

Chenjia XuSujuan Gao

PMID: 31929164

DOI: 10.3233/jad-191023

Abstract

Animal studies have shown that diet-induced hypercholesterolemia (HC) increases amyloid-β (Aβ) accumulation and accelerates Alzheimer's disease (AD) pathology. However, the association of HC with AD in human studies has not been consistently established. We aimed to investigate the rela...read more

Mentioned in this Paper

Plaque (Lesion)
Neuron Projection Morphogenesis
Cerebral Amyloid Angiopathy
Human Study
Alzheimer's Disease
APOE gene
Analysis
Diet
Autopsy
Neuropathology
1

Similar Papers Found In These Feeds

Alzheimer's Disease: APOE

Apolipoprotein E (APOE) polymorphic alleles are major genetic risk factors for Alzheimer's Disease. Discover the latest research on APOE and other genetic determinants of Alzheimer's Disease here.

Alzheimer's Disease: Neuroimaging

Alzheimer's disease (AD) is a chronic neurodegenerative disease. Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.

Related Papers

Journal of Alzheimer's Disease : JAD

Alzheimer's disease and head circumference

Journal of Alzheimer's Disease : JADApril 22, 2006
Patricio S EspinosaCharles D Smith
Paper Details
References
  • References34
  • Citations
1234
  • References34
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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