Association of lipid parameters and insulin resistance with bone health in South Korean adolescents

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
S-W ParkD-H Kim

Abstract

This study investigated the association between lipid profiles and insulin resistance and bone mineral content (BMC) in Korean adolescents and found that BMC was inversely associated with triglyceride (TG) and homeostasis model assessment of insulin resistance (HOMA-IR). This association did not differ according to obesity status in either boys or girls. To prevent future osteoporosis, it is important to identify factors that affect bone health in adolescents as well as adults. This study aimed to examine the association between lipid profiles and insulin resistance and BMC in Korean adolescents. Data from 706 boys and 621 girls, who participated in the Korea National Health and Nutrition Examination Survey from 2008 to 2011, were analyzed. Lipid profiles were measured, and HOMA-IR was calculated to assess insulin resistance. BMC was measured for the total femur, femur neck, and lumbar spine by using whole-body dual-energy X-ray absorptiometry (DXA). TG level and HOMA-IR were negatively correlated with BMC at all three sites in boys. In girls, TG level showed a negative correlation with BMC at the femur neck and lumbar spine, and HOMA-IR was negatively associated with BMC at the femur neck only. These inverse associations did n...Continue Reading

References

Jan 1, 1993·Calcified Tissue International·G D Roodman
Feb 1, 1993·The Journal of Clinical Endocrinology and Metabolism·K I BirkelandS Vaaler
Dec 1, 1996·Diabetes Care·E Barrett-Connor, D Kritz-Silverstein
Apr 4, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·B AbrahamsenH Beck-Nielsen
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
Jul 24, 2001·Archives of Internal Medicine·H KoshiyamaY Nakamura
Jun 26, 2002·Endocrine Journal·Toru YamaguchiKazuo Chihara
Sep 5, 2002·Biochemical and Biophysical Research Communications·Claus LangerArnold von Eckardstein
Jul 30, 2003·The American Journal of Clinical Nutrition·Robert P Heaney
Sep 26, 2003·Calcified Tissue International·L B TankòC Christiansen
Oct 11, 2003·Endocrine Research·Ling-Yi WuDee Pei
Dec 12, 2003·Calcified Tissue International·S AdamiE Battaglia
Dec 13, 2003·Arteriosclerosis, Thrombosis, and Vascular Biology·Yin TintutLinda L Demer
Dec 16, 2003·Obstetrics and Gynecology·Andrea PoliPier Giorgio Crosignani
Jul 13, 2004·The American Journal of Cardiology·Tiziana MontalciniArturo Pujia
Sep 17, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Lian-Hua CuiJin-Su Choi
Dec 28, 2005·The American Journal of Medicine·Daniel H SolomonPhilip S Wang
Apr 20, 2006·The Journal of Clinical Endocrinology and Metabolism·E M ClarkJ H Tobias
Apr 15, 2008·Trends in Endocrinology and Metabolism : TEM·Na Kyung Lee, Gerard Karsenty
Sep 23, 2008·European Journal of Endocrinology·Francesco Chiarelli, Maria Loredana Marcovecchio
Nov 20, 2008·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Nicholas J TimpsonJonathan H Tobias
Apr 14, 2009·Bone Marrow Transplantation·G A M FaulhaberT W Furlanetto
Apr 21, 2009·The American Journal of Medicine·Clifford J Rosen, Anne Klibanski
Apr 22, 2011·The Journal of Clinical Endocrinology and Metabolism·Norman K PollockCatherine L Davis
Jun 7, 2011·Journal of Bone and Mineral Metabolism·Hye Jin YooKyung Mook Choi
Apr 12, 2012·The Journal of Clinical Endocrinology and Metabolism·Debbie A LawlorJon H Tobias

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Citations

Jun 19, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Young-Gyun SeoKyung Hee Park

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