Association of Lower Adiponectin Plasma Levels, Increased Age and Smoking with Subclinical Atherosclerosis in Patients with HIV-1 Infection.

Current HIV Research
Philipe Quagliato BellinatiEdna Maria Vissoci Reiche

Abstract

The association between subclinical atherosclerosis and traditional cardiovascular disease (CVD) risk factors, inflammatory and metabolic biomarkers has been demonstrated around the world and specifically Brazilian human immunodeficiency virus type 1 (HIV-1)- infected individuals. However, the association between subclinical atherosclerosis and these aforementioned factors combined with anti-inflammatory biomarkers has not been examined in these populations. To evaluate the association of the carotid intima-media thickness (cIMT) with CVD risk factors, inflammatory, metabolic and HIV-1 infection markers combined with adiponectin and interleukin (IL)-10 as anti-inflammatory variables. In this case-control study, 49 HIV-1-infected patients on combined antiretroviral therapy (cART) and 85 controls were compared for traditional CVD risk factors, inflammatory, metabolic, and anti-inflammatory variables. Further, we compared HIV-1-infected patients according to their cIMT (as continuous and categorized <0.9 or ≥0.9 mm variable) visualized by carotid ultrasonography doppler (USGD). Twenty-four (48.9%) HIV-1-infected patients showed cIMT ≥0.9 mm. The patients had higher levels of C reactive protein on high sensitivity assay (hsCRP), tu...Continue Reading

References

Mar 27, 1999·Biochemical and Biophysical Research Communications·Y AritaY Matsuzawa
May 29, 2000·Scandinavian Journal of Infectious Diseases·S R Penzak, S K Chuck
Apr 8, 2003·The Journal of Clinical Endocrinology and Metabolism·Qiang TongGökhan S Hotamisligil
Aug 29, 2003·The Journal of Biological Chemistry·Hui ChenMichael J Quon
Sep 18, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David C RhewMatthew Bidwell Goetz
Jun 5, 2004·Annals of Epidemiology·Teri A ManolioUNKNOWN CHS Collaborative Research Group
Sep 17, 2004·Biochemical and Biophysical Research Communications·Anna M WolfHerbert Tilg
Jul 26, 2005·Biochemical and Biophysical Research Communications·Shinji SaijoYoshiro Kobayashi
Jul 18, 2006·Current Vascular Pharmacology·Katharina SchroecksnadelDietmar Fuchs
Mar 9, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Noriyuki Ouchi, Kenneth Walsh
Apr 26, 2007·The Journal of Clinical Endocrinology and Metabolism·Virginia A TriantSteven K Grinspoon
Sep 21, 2007·International Journal of Immunopathology and Pharmacology·K FalascaJ Vecchiet
Sep 25, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Donald P Kotler
Dec 17, 2008·AIDS Patient Care and STDs·Oluwatoyin AdeyemiNeena Thomas-Gossain
Aug 28, 2009·Seminars in Dialysis·Marcin AdamczakAndrzej Wiecek
Aug 29, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allison C RossGrace A McComsey
Apr 30, 2010·Current HIV Research·Katia FalascaJacopo Vecchiet
Jun 15, 2010·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Nina Friis-MøllerUNKNOWN DAD study group
Aug 25, 2010·European Cytokine Network·Douglas S Kwon, Daniel E Kaufmann
Jan 12, 2011·The Journal of Infectious Diseases·Robert C KaplanSteven G Deeks
Jul 16, 2011·Arteriosclerosis, Thrombosis, and Vascular Biology·Paul WelshUNKNOWN PROSPER Study Group
May 3, 2012·Stroke; a Journal of Cerebral Circulation·Marit HerderEllisiv B Mathiesen
Jun 21, 2012·Biochimie·Koji OhashiYuji Matsuzawa
Jul 17, 2012·Biochimie·M T Villarreal-Molina, B Antuna-Puente
Aug 10, 2012·AIDS·Kathleen V FitchSteven K Grinspoon
Oct 20, 2012·Arquivos brasileiros de cardiologia·Maria da Conceição Brandão de Arruda FalcãoHeloísa Ramos Lacerda
Jan 22, 2013·Atherosclerosis·George NtaiosGeorge N Dalekos

❮ Previous
Next ❯

Citations

Dec 8, 2021·Current Opinion in Infectious Diseases·Padraig McGettrick, Patrick W G Mallon

❮ Previous
Next ❯

Related Concepts

Related Feeds

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.