Association of Maternal Factors with Perinatal Complications in Pregnancies Complicated with Diabetes: A Single-Center Retrospective Analysis

Journal of Clinical Medicine
Sho EndoHiroshi Itoh

Abstract

The aim of this study was to clarify the association of maternal factors with perinatal complications in pregnancies complicated with type 1 (T1D) or type 2 diabetes (T2D). We conducted a retrospective chart review and enrolled 26 Japanese pregnant women with diabetes who received perinatal care at our hospital between 2008 and 2015. Perinatal complications were defined as one or more of the following: miscarriage, fetal death, fetal dysfunction, fetal structural anomaly, small-for-gestational age, large-for-gestational age (LGA), premature birth, neonatal hypoglycemia, pregnancy-induced hypertension (PIH), deterioration of maternal kidney function, and urgent Caesarean section (CS). The associations between perinatal complications and maternal factors were examined. Approximately 70% and 50% of women with T1D and T2D experienced perinatal complications, respectively. LGA, neonatal hypoglycemia, and urgent CS were major perinatal complications in women with T1D, while PIH and urgent CS were major complications in those with T2D. In women with T1D, pre-gestational HbA1c was significantly higher in women with perinatal complications than in those without. In women with T2D, pre-gestational body mass index was significantly higher...Continue Reading

References

Oct 1, 1994·Diabetes Research and Clinical Practice·Y OmoriM Sanaka
May 1, 2004·American Journal of Obstetrics and Gynecology·Joshua L WeissUNKNOWN FASTER Research Consortium
Jun 23, 2005·American Journal of Obstetrics and Gynecology·Oded LangerLois Brustman
Jul 26, 2007·BMC Public Health·Sohinee BhattacharyaSiladitya Bhattacharya
Jan 19, 2008·Diabetes Research and Clinical Practice·Annunziata LapollaDomenico Fedele
May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Oct 8, 2009·The Journal of Clinical Endocrinology and Metabolism·Montserrat BalsellsR Corcoy
Jan 12, 2011·Journal of Women's Health·Ammon HandisuryaAlexandra Kautzky-Willer
Jun 10, 2011·The Journal of Obstetrics and Gynaecology Research·Yoshio MatsudaShigeru Saito
Jan 4, 2013·Journal of Clinical and Diagnostic Research : JCDR·Anjana Verma, Lalit Shrimali
Aug 2, 2013·Journal of Obstetrics and Gynaecology of India·Deepika JainSushila Khuteta
Mar 13, 2014·Pediatrics International : Official Journal of the Japan Pediatric Society·Kazuo ItabashiYoshikazu Nakamura

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Citations

Mar 24, 2021·BMC Pregnancy and Childbirth·Valentina GuarnottaCarla Giordano

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Software Mentioned

Statistical Package for the Social Sciences ( SPSS Statistics

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