Abstract
We performed a meta-analysis to estimate whether combined evidence shows the association between the MCP-1-2518A/G polymorphism and susceptibility to autoimmune diseases. Relevant articles dated to July 2014 were acquired from the PubMed, EMBASE, ISI, and CNKI databases. The number of the genotypes and/or alleles for the MCP-1-2518A/G in cases and control subjects was extracted, and statistical analysis was conducted using STATA 11.2 software. Summary odds ratios (ORs) with their 95 % confidence intervals (95 % CIs) were used to calculate the risk of autoimmune diseases with the MCP-1-2518A/G. Significant increased risk of autoimmune diseases could be found for A allele vs. G allele (OR = 1.616, 95 % CI 1.027-2.542, P = 0.038) and AA + AG vs. GG (OR = 1.616, 95 % CI 1.027-2.542, P = 0.038) in Asian patients with rheumatoid arthritis (RA), and for A allele vs. G allele (OR = 1.383, 95 % CI 1.142-1.676, P = 0.022) and AA vs. AG + GG (OR = 1.575, 95 % CI 1.361-1.823, P < 0.001) in European patients with Crohn's disease (CD). In addition, when comparison of European patients with lupus nephritis (LN) and without LN, significant association between patients with LN and without LN also could be found for AA vs. AG + GG (OR = 0.713, 9...Continue Reading
References
Oct 1, 1993·Clinical Immunology and Immunopathology·M HarigaiS Kashiwazaki
May 3, 1996·Cell·T J Vyse, J A Todd
Jun 1, 1996·Journal of Leukocyte Biology·M C GrimmW F Doe
Feb 12, 1998·BMJ : British Medical Journal·M EggerA N Phillips
Dec 18, 1998·Human Genetics·J P LinR L Wilder
Jun 11, 1999·Biochemical and Biophysical Research Communications·B H RovinR Saxena
Feb 15, 2002·Tissue Antigens·F AguilarA Núñez-Roldán
Oct 3, 2002·European Journal of Immunogenetics : Official Journal of the British Society for Histocompatibility and Immunogenetics·S-Y HwangH-Y Kim
Dec 3, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Hyun Lee KimYo Su Kim
Dec 11, 2002·The Journal of Pathology·Charmian BanksNick Sheron
Jun 27, 2003·Human Immunology·Maria Francisca González-EscribanoAntonio Núñez-Roldán
Aug 9, 2003·International Journal of Colorectal Disease·Hans HerfarthGerhard Rogler
Feb 10, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Oliver M SteinmetzRolf A K Stahl
Mar 31, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·K F TaitS C L Gough
May 4, 2004·Lupus·H NakashimaM Harada
Jun 10, 2004·Arthritis and Rheumatism·Marco TucciHanno B Richards
Dec 22, 2004·Archives of Dermatological Research·Dong Qing YeXue Jun Zhang
Jan 19, 2005·The Journal of Investigative Dermatology·Sigrid KarrerClaus Hellerbrand
Dec 20, 2005·Clinical and Experimental Nephrology·Honami MoriFumitake Gejyo
May 25, 2006·BMC Medical Genetics·Elena SánchezBobby P Koeleman
Jun 9, 2006·Rheumatology·Y H LeeJ B Harley
Oct 21, 2006·Lancet Neurology·Lisa F BarcellosStephen L Hauser
Jan 15, 2008·Human Immunology·Guadalupe LimaLuis Llorente
Feb 26, 2008·Autoimmunity Reviews·Paolo BoscoloPio Conti
May 31, 2008·Journal of Autoimmunity·Grant MorahanRob Williams
Jul 8, 2008·Autoimmunity Reviews·Ana LleoMauro Podda
Nov 27, 2008·Human Immunology·Timothy R D J RadstakeMarieke J H Coenen
Aug 18, 2009·Journal of Autoimmunity·Pietro Invernizzi, M Eric Gershwin
Feb 4, 2010·The American Journal of Gastroenterology·O PalmieriVito Annesec
Mar 17, 2010·The Journal of Rheumatology·Patricia MalafronteViktoria Woronik
Apr 9, 2010·International Journal of Rheumatic Diseases·Ashraf AlzawawyMona Eldalie
Aug 5, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Stephen D MarksKjell Tullus
Nov 26, 2010·Arthritis Research & Therapy·Juan-Manuel Anaya
Jul 27, 2011·Biochemical Society Transactions·Lars VereeckeGeert van Loo
Apr 3, 2012·European Cytokine Network·Federico ArandaGabriela de Larrañaga
Jun 21, 2012·Molecular Biology Reports·Ya-Ling LiangXiao-Dong Xie
Jun 6, 2013·Autoimmunity·Han CenDong-Qing Ye
Citations
Aug 18, 2016·Clinical Rheumatology·Emilia Saint MartinGustavo Citera
Oct 28, 2017·Lupus·J A Gómez-PuertaG Vásquez
Jun 9, 2020·Experimental and Therapeutic Medicine·Alexandra ChiraDan Lucian Dumitrascu
May 4, 2018·Mediators of Inflammation·Nina JönssonSophie Ohlsson
Jul 16, 2020·International Journal of Molecular Sciences·Dmitry S MikhaylenkoAndrey A Zamyatnin
Aug 28, 2021·Cells·Leszek Roszkowski, Marzena Ciechomska
Aug 31, 2021·Current Eye Research·Maryam Ghaffari LalehMehdi Yaseri
Nov 10, 2021·Immunity, Inflammation and Disease·Pardis-Sadat Tabatabaei-PanahReza Akbarzadeh