Association of Medication Beliefs, Self-efficacy, and Adherence in a Diverse Cohort of Adults with Rheumatoid Arthritis

The Journal of Rheumatology
Caroline McCulleyJennifer L Barton

Abstract

Rheumatoid arthritis (RA) patients' adherence to disease-modifying antirheumatic drugs (DMARD) is often suboptimal. We examined associations among medication beliefs, self-efficacy, and adherence to medications in RA. Data were from a longitudinal observational cohort of persons with RA. Subjects completed telephone interviews on self-reported adherence, self-efficacy, demographics, and the Beliefs about Medicines Questionnaire (BMQ), which assesses beliefs in necessity and beliefs about taking medication. Bivariate and multivariate logistic regression identified correlates of poor adherence to synthetic DMARD and prednisone as well as to biologic therapy, including medication concerns and necessity. There were 362 patients who reported taking a synthetic DMARD and/or prednisone. Of these, 14% and 21% reported poor adherence to oral DMARD or prednisone, and biologics, respectively. There were 64% who reported concern about taking medicines, 81% about longterm effects, and 47% about becoming too dependent on medicines. In multivariate analyses, the BMQ necessity score was independently associated with better adherence to oral DMARD or prednisone (adjusted OR 0.61, 95% CI 0.41-0.91), while self-efficacy was associated with greate...Continue Reading

References

Feb 1, 1980·Arthritis and Rheumatism·J F FriesH R Holman
Feb 8, 2000·Journal of Psychosomatic Research·R Horne
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Dec 11, 2002·JAMA : the Journal of the American Medical Association·R Brian HaynesAmit X Garg
Aug 3, 2006·Journal of General Internal Medicine·Lorraine S WallaceBarry D Weiss
Sep 21, 2006·The Annals of Pharmacotherapy·Hemant M Phatak, Joseph Thomas
Mar 13, 2008·Journal of General Internal Medicine·Lisa D ChewMichelle Vanryn
Jan 30, 2009·Arthritis and Rheumatism·Laura J JulianPatricia Katz
Mar 21, 2009·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Margaret E GattiSunil Kripalani
Sep 30, 2009·Archives of Internal Medicine·Rebecca J MullanSteven A Smith
Aug 3, 2010·International Journal of Clinical Rheumatology·Sofia de Achaval, Maria E Suarez-Almazor
Jan 26, 2011·Journal of Psychosomatic Research·Benjamin SchüzClemens Tesch-Römer
Apr 12, 2012·Health Education & Behavior : the Official Publication of the Society for Public Health Education·Fatima Al SayahJeffrey A Johnson
May 23, 2012·Expert Review of Clinical Immunology·Bart J F van den BemtCornelia H M van den Ende
Sep 25, 2012·Research in Social & Administrative Pharmacy : RSAP·Olayinka O ShiyanbolaElizabeth Chrischilles
Dec 5, 2014·The American Journal of the Medical Sciences·Mohsen A GadallahDonald E Morisky

❮ Previous
Next ❯

Citations

Feb 21, 2021·ACR Open Rheumatology·Gabriella VenterCatherine L Hill
Dec 3, 2020·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Roland DuculanCarol A Mancuso
Nov 24, 2021·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Claire C ConleySuzanne C O'Neill

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.