Association of mood disorders with cardiovascular disease risk factors in overweight and obese youth with elevated blood pressure.

The Journal of Clinical Hypertension
Leah MedranoTammy M Brady

Abstract

The American Heart Association defines mood disorders (MDO) as a tier-II cardiovascular disease risk factor in children. Cross-sectional analysis of overweight/obese children referred to an obesity hypertension clinic revealed 37% had a MDO (defined by clinical diagnosis or Patient Health Questionnaire-9/-A score ≥10), 55% had confirmed hypertension, and 75% left ventricular hypertrophy (LVH). Children with MDOs were older, had greater measures of adiposity, and had a greater prevalence of hypertension (78%) than those without MDOs (42%; P = .04). Hypertensive children were 2.8 times more likely to have a MDO than those without (52% vs 18%; P = .02). Multivariable logistic regression revealed a statistically significant independent association of MDOs with hypertension (Odds Ratio [OR] 6.3, P = .048), but not LVH (LVMI ≥ 51 g/m2.7 ; OR 1.13, P = .88). Overall, the prevalence of MDOs in this group of overweight/obese children with elevated blood pressure was well above national averages, suggesting that at-risk youth, particularly those with confirmed hypertension, should be regularly screened for MDOs.

References

Oct 12, 1999·Journal of the American Academy of Child and Adolescent Psychiatry·B BirmaherM Baugher
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Mar 1, 2002·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Jeffrey G JohnsonJanet B W Williams
Feb 27, 2003·Child: Care, Health and Development·C GlazebrookL Coates
Aug 2, 2003·Biological Psychiatry·Albert J StunkardKelly C Allison
Oct 16, 2003·Journal of the American Academy of Child and Adolescent Psychiatry·Rhonda C BoydKarren D M Campbell
May 15, 2004·Medical Hypotheses·Roland Rosmond
Aug 3, 2004·Pediatrics·UNKNOWN National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents
Jul 1, 2006·Journal of General Internal Medicine·Frederick Y HuangRobert L Spitzer
Jul 5, 2006·Archives of Pediatrics & Adolescent Medicine·Rachel A Zuckerbrot, Peter S Jensen
Jul 25, 2006·The American Journal of Cardiology·Shanthi SivanandamJulia Steinberger
Jun 19, 2007·Psychoneuroendocrinology·Jorge I Castillo-QuanJulia M Pérez-Osorio
Mar 19, 2008·The Journal of Pediatrics·Albane B R MaggioNathalie J Farpour-Lambert
Nov 11, 2008·Journal of Lipid Research·Alice H Lichtenstein
Mar 24, 2009·Journal of Psychosomatic Research·Ann Christin RivenesArnstein Mykletun
May 9, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Philip R KhouryThomas R Kimball
Jul 30, 2009·Current Opinion in Cardiology·Alison M HillPenny M Kris-Etherton
Aug 7, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Elise C Cope, Cathy W Levenson
Sep 22, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Kathleen Ries MerikangasJoel Swendsen
Apr 13, 2011·Acta Psychiatrica Scandinavica·G Parker, H Brotchie
Apr 20, 2011·The Australian and New Zealand Journal of Psychiatry·Kristy SandersonAlison J Venn
Jun 22, 2012·Psychoneuroendocrinology·Arianne K B van Reedt DortlandFrans G Zitman
Aug 27, 2013·Psychiatric Annals·Deina NemiaryKisha Holden
Sep 13, 2013·Journal of Child and Adolescent Psychopharmacology·Brandon MansoorDavid Brent
Sep 1, 2015·Clinical Therapeutics·Nicole L Mihalopoulos, Michael G Spigarelli
Nov 5, 2015·The Journal of Clinical Hypertension·Tammy M BradyEdgar R Miller
Nov 19, 2015·The Journal of Clinical Psychiatry·William H CoryellChadi A Calarge
Sep 30, 2016·Prevention Science : the Official Journal of the Society for Prevention Research·Idia B ThurstonTracy K Richmond
Oct 9, 2016·The International Journal of Behavioral Nutrition and Physical Activity·Erin HoareSteven Allender
Aug 23, 2017·Pediatrics·Joseph T FlynnUNKNOWN SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN

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Citations

Feb 13, 2019·Current Hypertension Reports·Edem Binka, Tammy M Brady
Feb 12, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Fernanda Barrinha FernandesDulce Elena Casarini
Apr 24, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Anne E DawsonCamille S Wilson

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