Association of obstructive sleep apnea risk factors with nocturnal enuresis in postmenopausal women

Menopause : the Journal of the North American Menopause Society
Patrick KooCharles B Eaton

Abstract

The prevalence of obstructive sleep apnea (OSA) in women increases significantly after menopause. However, identifying at-risk women is difficult because they tend to underreport symptoms and their complaints may differ from those traditionally associated with OSA. We investigated whether OSA risk factors are associated with the presence of a "nontraditional" complaint, such as nocturnal enuresis, in postmenopausal women. A cross-sectional study of postmenopausal women aged 50 to 79 years who participated in the Women's Health Initiative Observational Study and clinical trials (1993-2005) at 40 clinical centers in the United States was performed. Multiple variable logistic regression analysis was used to determine the association of OSA risk factors with nocturnal enuresis. A cohort of 2,789 women (1.7%) reported having nocturnal enuresis. Obesity (odds ratio [OR], 2.29; 95% CI, 2.00-2.62), snoring (OR, 2.01; 95% CI, 1.74-2.32), poor sleep quality (OR, 1.70; 95% CI, 1.52-1.91), sleep fragmentation (OR, 2.44; 95% CI, 2.14-2.79), daytime sleepiness (OR, 1.50; 95% CI, 1.33-1.68), and hypertension (OR, 1.13; 95% CI, 1.01-1.26) were associated with nocturnal enuresis. Each additional OSA risk factor in a predefined OSA score signifi...Continue Reading

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Citations

May 6, 2016·Frontiers in Aging Neuroscience·Farnoosh EmamianAmir A Sepehry
Nov 1, 2017·Menopause : the Journal of the North American Menopause Society·Catherine C GaoStephanie S Faubion
Jun 29, 2017·Female Pelvic Medicine & Reconstructive Surgery·Cara NinivaggioSara B Cichowski
Jul 1, 2020·Terapevticheskiĭ arkhiv·L I KolesnikovaI M Madaeva
Jun 9, 2020·Current Urology Reports·Eric G Katz, Lara S MacLachlan
Oct 7, 2020·Sleep Medicine Reviews·Claudio LiguoriBiancamaria Guarnieri
Jun 18, 2018·American Journal of Lifestyle Medicine·Megan Doyle-McClamPatrick Koo

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