Association of paraspinal muscle water-fat MRI-based measurements with isometric strength measurements

European Radiology
Sarah SchlaegerThomas Baum

Abstract

Chemical shift encoding-based water-fat MRI derived proton density fat fraction (PDFF) of the paraspinal muscles has been emerging as a surrogate marker in subjects with sarcopenia, lower back pain, injuries and neuromuscular disorders. The present study investigates the performance of paraspinal muscle PDFF and cross-sectional area (CSA) in predicting isometric muscle strength. Twenty-six healthy subjects (57.7% women; age: 30 ± 6 years) underwent 3T axial MRI of the lumbar spine using a six-echo 3D spoiled gradient echo sequence for chemical shift encoding-based water-fat separation. Erector spinae and psoas muscles were segmented bilaterally from L2 level to L5 level to determine CSA and PDFF. Muscle flexion and extension maximum isometric torque values [Nm] at the back were measured with an isokinetic dynamometer. Significant correlations between CSA and muscle strength measurements were observed for erector spinae muscle CSA (r = 0.40; p = 0.044) and psoas muscle CSA (r = 0.61; p = 0.001) with relative flexion strength. Erector spinae muscle PDFF correlated significantly with relative muscle strength (extension: r = -0.51; p = 0.008; flexion: r = -0.54; p = 0.005). Erector spinae muscle PDFF, but not CSA, remained a statis...Continue Reading

References

Apr 1, 1991·AJR. American Journal of Roentgenology·F G ShellockV R Edgerton
Nov 1, 1983·AJR. American Journal of Roentgenology·H HadarM Heifetz
Jan 1, 1995·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C C GlüerH K Genant
Jan 1, 1994·European Journal of Applied Physiology and Occupational Physiology·H TakahashiY Itai
Jan 1, 1993·European Journal of Applied Physiology and Occupational Physiology·A E MillerD G Sale
Feb 24, 2001·Journal of Manipulative and Physiological Therapeutics·C E MoreauS R Moreau
May 18, 2001·Journal of Applied Physiology·B H GoodpasterA B Newman
Sep 13, 2003·Journal of Applied Physiology·Timothy J Doherty
Aug 5, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Gregory E HicksFrances A Tylavsky
Oct 18, 2005·Journal of Manipulative and Physiological Therapeutics·Christopher J Colloca, Richard N Hinrichs
Nov 2, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Bret H GoodpasterAnne B Newman
Apr 1, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Dimitrios C KarampinosSharmila Majumdar
May 17, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Timothy StarkRandy Beck
Dec 1, 2011·Journal of Magnetic Resonance Imaging : JMRI·Dimitrios C KarampinosSharmila Majumdar
Oct 5, 2013·Medicine and Science in Sports and Exercise·Maryse FortinMichele C Battié
Mar 29, 2014·Muscle & Nerve·Andrew C SmithJames M Elliott
Aug 22, 2014·Neurology·Julia R DahlqvistJohn Vissing
Apr 2, 2015·The Spine Journal : Official Journal of the North American Spine Society·Andrew J TeichtahlFlavia M Cicuttini
Apr 9, 2015·The Proceedings of the Nutrition Society·Steven B HeymsfieldJolene Zheng
Dec 5, 2015·AJNR. American Journal of Neuroradiology·R J CrawfordE J Ulbrich
Jul 28, 2016·BMC Musculoskeletal Disorders·Yogesh Kumar, Daichi Hayashi
Sep 2, 2016·PloS One·Alberto Mendez-VillanuevaValter Di Salvo
Oct 21, 2016·Medicine and Science in Sports and Exercise·Julia R DahlqvistJohn Vissing
Dec 15, 2016·Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine·Ralf RothOliver Faude

❮ Previous
Next ❯

Citations

Aug 31, 2019·Journal of Strength and Conditioning Research·Ryosuke Itoh, Norikazu Hirose
Oct 15, 2019·Pain Practice : the Official Journal of World Institute of Pain·Scott D TagliaferriDaniel L Belavy
Mar 25, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E BurianT Baum
Mar 8, 2020·European Radiology·Silvia Karem Janet Flores QuispeChiara Giraudo
Jun 25, 2020·Journal of Orthopaedic Surgery and Research·Wei WangZhongqiang Chen
Jun 8, 2021·Frontiers in Neurology·Aisha M SheikhJohn Vissing
Sep 15, 2021·PloS One·Waruna L PeirisDonna M Urquhart
Nov 14, 2021·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Han GengyuLi Weishi
Jan 4, 2022·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jun-Zhe DingGuo-Gunag Zhao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.