Association of parental eczema, hayfever, and asthma with atopic dermatitis in infancy: birth cohort study

Archives of Disease in Childhood
N Wadonda-KabondoALSPAC Study Team

Abstract

To evaluate the association of parental history of atopic disease with childhood atopic dermatitis, and to examine the relative strength of associations with maternal and paternal disease. Mothers were recruited to the Avon longitudinal study of parents and children (ALSPAC) from the eighth week of pregnancy. Before parturition, both parents were asked, separately, to report their lifetime history of eczema, asthma, and hayfever. Parents reported symptoms of atopic dermatitis in their children at ages 6, 18, 30, and 42 months. Of 8530 children with complete information on rash at ages 6, 18, 30, and 42 months, 7969 had complete information on maternal atopic disease and 5658 on maternal and paternal atopic disease. There was a strong association between parental eczema and childhood atopic dermatitis: odds ratio 1.69 (95% confidence interval, 1.47 to 1.95) for maternal eczema only, 1.74 (1.44 to 2.09) for paternal eczema only, and 2.72 (2.09 to 3.53) for eczema in both parents. Associations with parental asthma or hayfever were attenuated after controlling for parental eczema. There was no evidence that associations with maternal atopy were stronger than with paternal. Associations between parents' atopic disease and the risk o...Continue Reading

References

Jul 1, 1977·Acta paediatrica Scandinavica·N I Kjellman
Dec 1, 1992·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M F MoffattJ M Hopkin
Aug 1, 1992·Archives of Disease in Childhood·S DoldE Stiepel
Jul 1, 1989·Paediatric and Perinatal Epidemiology·A M AngioniC Corchia
Mar 1, 1989·Acta paediatrica Scandinavica·N AbergU Lindberg
Jun 1, 1982·Journal of Epidemiology and Community Health·D M FergussonF T Shannon
Jul 1, 1981·Clinical Allergy·D M FergussonB Taylor
Jun 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S H ArshadD W Hide
Apr 16, 1998·The British Journal of Dermatology·H E CoxJ I Harper
Jun 26, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M F Moffatt, W O Cookson
Oct 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N Aberg
Feb 13, 2002·European Journal of Human Genetics : EJHG·A HaagerupT A Kruse
Jul 18, 2002·Allergy·A HaagerupT A Kruse
Nov 25, 2003·The British Journal of Dermatology·N Wadonda-KabondoUNKNOWN ALSPAC Study Team

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Citations

Jun 12, 2009·Human Genetics·Ulla ChristensenAnders D Børglum
Mar 13, 2008·Indian Journal of Pediatrics·Z PourpakM Moin
Sep 27, 2008·Archives of Disease in Childhood·B AlmG Wennergren
Nov 30, 2011·International Archives of Allergy and Immunology·Qiu-Ping WangBing-Ling Wang
Dec 19, 2008·Croatian Medical Journal·Anzhela V Glushkova, Andrej M Grjibovski
Sep 18, 2007·Current Opinion in Allergy and Clinical Immunology·Sonja Bonness, Thomas Bieber
May 25, 2013·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C Karila
May 23, 2012·The Journal of Allergy and Clinical Immunology·S Hasan ArshadSusan L Ewart
Mar 9, 2012·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Meital Portugal-CohenRon Kohen
Aug 27, 2010·The Journal of Pediatrics·Jocelyn M Biagini Myers, Gurjit K Khurana Hershey
Feb 12, 2009·The Journal of Investigative Dermatology·Sara J Brown, W H Irwin McLean
Jul 16, 2008·Seminars in Cutaneous Medicine and Surgery·Sara J Brown, Alan D Irvine
Nov 1, 2006·Allergy·A BockelbrinkUNKNOWN LISA Study Group
Oct 22, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Kaisa PyrhönenEsa Läärä
Aug 26, 2014·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A R MorganL R Ferguson
Dec 3, 2013·Journal of the American Academy of Dermatology·Lawrence F EichenfieldRobert Sidbury
Mar 18, 2015·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Gareth MarlowAngharad R Morgan
Jun 5, 2012·The Journal of Allergy and Clinical Immunology·Marie-Hélène DizierFlorence Demenais
May 17, 2014·PloS One·Lise MoussuJocelyne Just
Jun 15, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Alexandra R VaughnVivian Y Shi
Apr 17, 2020·PloS One·Samantha RadaEva S Schernhammer
Jul 9, 2020·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·Ann-Marie Malby SchoosHans Bisgaard
Apr 5, 2017·International Journal of Epidemiology·Shah EbrahimGeorge Davey Smith
Jan 26, 2018·International Journal of Dermatology·Yuval KriegerAsnat Walfisch
May 16, 2018·Dermatitis : Contact, Atopic, Occupational, Drug·Yi-Yeong GohYik Ling Chew
Jun 23, 2018·Nature Reviews. Disease Primers·Stephan WeidingerAlan D Irvine
Nov 24, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P Margaritte-JeanninM-H Dizier
Apr 4, 2018·Pediatrics in Review·Andrea R WaldmanLawrence F Eichenfield
Mar 9, 2018·Immunity, Inflammation and Disease·David Ferrandiz-MontDar-Der Ji
Jan 9, 2020·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·F A SendrasoaF Rapelanoro Rabenja
Oct 14, 2020·Current Allergy and Asthma Reports·Shanthi Narla, Jonathan I Silverberg
Jul 19, 2019·The Journal of Allergy and Clinical Immunology. in Practice·Kim M A EndreUNKNOWN study group
May 1, 2021·International Journal of Molecular Sciences·Jowita Sroka-Tomaszewska, Magdalena Trzeciak
Jun 17, 2019·Dermatology : International Journal for Clinical and Investigative Dermatology·Mari LøsetKristian Hveem
Nov 18, 2021·Annals of Medicine·Shanthi Narla, Jonathan I Silverberg

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