Abstract
Periodontal disease and systemic health are closely associated. However, there is no data supporting the association between periodontal disease and patients with liver diseases associated with hepatitis C virus (HCV) and/or hepatitis B virus (HBV) infection. The aim of this study was to evaluate the association between periodontitis and progression of liver diseases in patients with HCV and/or HBV infection. In this retrospective study, 351 patients with HCV- and/or HBV-related liver diseases underwent screening for periodontal disease using the Salivaster® salivary occult blood test from February 2010 to June 2014. Furthermore, we examined the prevalence of fimbrillin (fimA) genotype of Porphyromonas gingivalis (P. gingivalis) in 28 HCV-infected patients visited at our hospital between January 2013 and June 2014. P. gingivalis with fimA genotype with types I to V was further detected using a PCR method. Of 351 patients, 76 patients (group 1) had a strong positive result for salivary occult blood test and 275 patients (group 2) had weak positive or negative test results. Significant factors between the groups were obesity, level of AST, ALT, LDH, ALP, Alb, D.Bil, T.cho, AFP, platelets (Plt), IRI, HOMA-IR, current interferon (I...Continue Reading
References
Mar 1, 1990·Journal of Periodontal Research·G R PerssonR C Page
Jan 1, 1985·Archives of Oral Biology·H Ben-AryehE Ben-Porath
Jul 1, 1994·Advances in Dental Research·G Embery, R Waddington
Jan 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·G DusheikoP Simmonds
Oct 1, 1996·Journal of Periodontology·J BeckS Offenbacher
Mar 12, 1998·Journal of Clinical Periodontology·S S SocranskyR L Kent
Apr 16, 1999·Journal of Clinical Microbiology·A AmanoS Hamada
Jul 31, 1999·Annals of Internal Medicine·H YoshidaM Omata
Jul 29, 2000·Journal of Clinical Periodontology·E Kaufman, I B Lamster
Nov 4, 2000·Journal of Clinical Microbiology·S C LeeM Rosenstraus
Jan 5, 2001·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Y NagaoM Sata
Feb 24, 2001·Journal of Periodontology·M MaticicU Skaleric
Oct 24, 2001·Journal of Dental Research·F Nishimura, Y Murayama
Dec 19, 2001·Infection and Immunity·Ichiro NakagawaShigeyuki Hamada
Jul 16, 2002·Oral Diseases·L HendersonJ Bagg
Jul 30, 2002·Gastroenterology·Haruhiko YoshidaMasao Omata
Sep 5, 2002·Microbiology and Molecular Biology Reviews : MMBR·Paul E KolenbranderRobert J Palmer
Mar 9, 2004·Journal of Clinical Microbiology·Kazuyuki IshiharaKatsuji Okuda
Jun 24, 2004·Oral Microbiology and Immunology·C G MissailidisM P A Mayer
Oct 28, 2004·Gastroenterology·Kendo KiyosawaEiji Tanaka
Aug 3, 2006·Journal of Periodontology·Brian L MealeyUNKNOWN American Academy of Periodontology
Dec 15, 2006·The Bulletin of Tokyo Dental College·Masanori HashimotoToshihide Noguchi
Mar 9, 2007·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Dorothea SizmannReiner Babiel
Apr 10, 2008·Journal of Gastroenterology and Hepatology·Yumiko NagaoMichio Sata
Aug 23, 2008·Microbiological Research·Kenichi TadokoroHirokazu Oguchi
Feb 20, 2009·Journal of Gastroenterology·Takeji UmemuraKendo Kiyosawa
Feb 24, 2009·Liver International : Official Journal of the International Association for the Study of the Liver·Lawrence Serfaty, Jacqueline Capeau
Aug 5, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yasuhiro AsahinaNamiki Izumi
Aug 18, 2010·Virology Journal·Yumiko Nagao, Michio Sata
Feb 22, 2012·BMC Gastroenterology·Masato YonedaAtsushi Nakajima
Oct 13, 2012·BMC Gastroenterology·Kazumi YamasakiSatoshi Shirahama
Apr 23, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hashem B El-Serag, Fasiha Kanwal
Jun 5, 2014·Ciência & saúde coletiva·Patrícia Garcia de Moura-GrecSilvia Helena de Carvalho Sales-Peres
Oct 1, 1996·Journal of Periodontology·James BeckSteven Offenbacher
Citations
Oct 27, 2015·Acta Biomaterialia·Govinda BhattaraiJeong-Chae Lee
May 7, 2015·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yuno OmuraKazuaki Chayama
Feb 26, 2016·Journal of Clinical Periodontology·Takaaki TomofujiManabu Morita
Jul 22, 2016·Anaesthesia·S Y HamS Na
Sep 27, 2016·Journal of Periodontology·Daniel Fernando Pereira VasconcelosJefferson Soares de Oliveira
Jan 16, 2016·SAGE Open Medicine·Lea Ladegaard Grønkjær
Nov 12, 2017·BMC Veterinary Research·Ilaria IacopettiRebecca Ricci
Oct 26, 2018·Clinical Oral Investigations·Mohammad Sultan AlakhaliEsam Halboub
Apr 13, 2017·Scientific Reports·Mihee HongYoung Bok Lee
Jan 7, 2016·Iranian Red Crescent Medical Journal·Mohammad Saeid Rezaee-ZavarehSeyed Moayed Alavian
Oct 22, 2019·Biomedical Reports·Yumiko Nagao, Takeshi Tanigawa
Jan 14, 2017·World Journal of Gastroenterology : WJG·Chong-Yang ZhangChun-Xu Wang
May 5, 2018·Journal of Immunology Research·Dorin Nicolae GheorgheIon Rogoveanu
Dec 14, 2018·Biomedicines·Hiba MohammedVincenzo Rocchetti
Oct 6, 2017·JCI Insight·Chathur AcharyaJasmohan S Bajaj
Sep 14, 2019·Infectious Agents and Cancer·Xiao-Bo LiuQiang Tong
Feb 13, 2018·United European Gastroenterology Journal·Lea Ladegaard GrønkjærHendrik Vilstrup
Feb 9, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Lea Ladegaard GrønkjærHendrik Vilstrup
Sep 15, 2018·Medicine·Donghyoun LeeHo-Kyung Chun
May 1, 2021·Cancers·Se-Young ParkNa-Young Song
Aug 20, 2021·Odontology·Steeve BregaintAnne Jolivet-Gougeon