Association of pre mortem diagnosis and autopsy findings in pediatric intensive care unit versus emergency department versus ward patients

Critical Care Medicine
B GoldsteinJ S Rubenstein

Abstract

As part of the overall quality assurance program for the Department of Pediatrics, we determined whether there were differences in the rates of unexpected autopsy findings between pediatric intensive care unit (ICU), emergency department, and ward patients. Prospective, descriptive study. Tertiary care children's hospital. Pediatric deaths (n = 212). None. Autopsies were obtained more frequently in emergency department patients (27/29 [93%]) compared with pediatric ICU (88/121 [73%] and ward (42/62 [68%]) patients (p = .03). The medical examiner's cases were more frequently from emergency department patients (22/27 [81%]) compared with pediatric ICU (39/88 [44%]) or ward (11/42 [26%]) patients (p < .001). We found unexpected autopsy findings in 19 (12%) of 157 patients. There were no unexpected findings from the medical examiner's cases. The most common unexpected findings were unidentified infections (n = 7 [three fungal, three viral, and one nonspecific]) and unrecognized cardiac malformations (n = 4). Unexpected findings occurred more frequently in pediatric ICU patients (16/88 [18%]) vs. emergency department (2/27 [7%]) or ward (1/42 [2%]) patients (p = .03). The occurrence rates of major unexpected findings (Class I and II...Continue Reading

References

Dec 1, 1977·The Journal of Pathology·F Hartveit
Aug 17, 1978·The New England Journal of Medicine·W C Roberts
Jul 17, 1987·JAMA : the Journal of the American Medical Association·R M BattleR E Anderson
Apr 1, 1985·Scandinavian Journal of Gastroenterology·K GibińskiD Koturbasz
Sep 1, 1974·Acta Medica Scandinavica·M Britton
Jan 1, 1983·Forensic Science International : Synergy·S AsnaesC Fenger
Apr 28, 1983·The New England Journal of Medicine·L GoldmanM Weisberg
Sep 1, 1981·The American Journal of Forensic Medicine and Pathology·M A Clark
Oct 11, 1980·British Medical Journal·H M CameronH Watson
Sep 6, 1965·JAMA : the Journal of the American Medical Association·J B HAZARD

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Citations

Mar 24, 2004·Resuscitation·Peter VanbrabantMarc Sabbe
Dec 5, 2009·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Kentaro SakaiKimiharu Iwadate
Aug 4, 2006·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Marta P CardosoEduardo J Troster
Sep 9, 2006·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Pablo Minces, Eduardo Schnitzler
Feb 10, 2004·Journal of the American Veterinary Medical Association·Michael S KentBruce R Madewell
Apr 30, 2013·Journal of Forensic and Legal Medicine·B KubatE Thoonen
Nov 11, 2008·Pediatric Transplantation·Abdulkader Al-RezqiUpton Allen
Dec 16, 2016·Virchows Archiv : an International Journal of Pathology·Raphael WidmannPeter K Bode
Jan 27, 2017·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Maria Caridad DavalosHardeep Singh
Feb 8, 2018·Cardiology in the Young·Priya N BhatAndrew Y Shin
Aug 7, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Benedict T GriffithsJoe Brierley
Sep 22, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Sonali BasuUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Resear
Jul 29, 2017·Der Pathologe·A-K RodewaldH Moch
Oct 21, 2014·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jason W CusterDavid E Newman-Toker
Jan 5, 2021·Virchows Archiv : an International Journal of Pathology·Nikhil RaghuramLillian Sung
Dec 8, 2006·Archives of Pathology & Laboratory Medicine·Melissa W Taggart, Randall Craver
Jun 23, 2001·Archives of Pathology & Laboratory Medicine·D M GrzybickiS S Raab
Oct 27, 2004·Archives of Pathology & Laboratory Medicine·David NewtonAmy Lowichik
Oct 24, 2018·Neonatology·Joline L H de SévauxFloris Groenendaal

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